4 Star Hotels in Santa Cruz, Santa Cruz

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Check availability on Santa Cruz 4 Star Hotels

Top Santa Cruz 4 Star Hotels

Marriott Santa Cruz de la Sierra Hotel
Outdoor pool, pool umbrellas, pool loungers

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
9.0 out of 10, Wonderful, (173)
"Hot water didn’t come on during the first morning and calling the front desk went unanswered. I had to go down to the front desk. Issue was resolved but it was still inconvenient. Fortunately there were no more unwanted surprises."
The price is €100
includes taxes & fees
25 Jan - 26 Jan
Marriott Santa Cruz de la Sierra Hotel
Camino Real Hotel
Indoor pool, outdoor pool, pool umbrellas

Camino Real Hotel

4.5 star property
8.8 out of 10, Excellent, (364)
"Great place to stay at, really good location and the staff is super helpful and kind "
The price is €111
includes taxes & fees
28 Jan - 29 Jan
Camino Real Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
2 outdoor pools

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
9.0 out of 10, Wonderful, (310)
"Very good quality hotel in beautiful Santa Cruz, Bolivia. Friendly staff Clean grounds "
The price is €126
includes taxes & fees
11 Feb - 12 Feb
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Breakfast, lunch and dinner served

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
9.2 out of 10, Wonderful, (217)
"Very nice accommodations, clean, very friendly and helpful staff"
The price is €72
includes taxes & fees
26 Jan - 27 Jan
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
TRYP by Wyndham Santa Cruz
Outdoor pool, open 9:00 AM to 10:00 PM, free pool cabanas

TRYP by Wyndham Santa Cruz

4.0 star property
9.4 out of 10, Exceptional, (103)
"Great stay! Wish they’d use the top floor as a work area as well, amazing view. Nice pool."
The price is €89
includes taxes & fees
25 Jan - 26 Jan
TRYP by Wyndham Santa Cruz
Sun Hotel
Outdoor pool

Sun Hotel

3.5 star property
8.2 out of 10, Very good, (276)
"Amazing place!!!"
The price is €104
includes taxes & fees
27 Jan - 28 Jan
Sun Hotel
Hotel LP Equipetrol
Front of property – evening/night

Hotel LP Equipetrol

3.5 star property
8.2 out of 10, Very good, (197)
"O quarto é amplo, super limpo, chuveiro ótimo, roupa de cama e toalhas bem limpas, funcionários são simpáticos. Não gostei do café da manhã e a internet é péssima. Localização também é ótima. "
The price is €64
includes taxes & fees
23 Jan - 24 Jan
Hotel LP Equipetrol
Ibis Santa Cruz DE LA Sierra
Sports facility

Ibis Santa Cruz DE LA Sierra

3.0 star property
9.6 out of 10, Exceptional, (37)
"Predictable, good vibe. Very good bed."
The price is €48
includes taxes & fees
2 Feb - 3 Feb
Ibis Santa Cruz DE LA Sierra
Hotel G
Comfort Room | Private kitchen

Hotel G

3.5 star property
7.8 out of 10, Good, (102)
"excelente ubicación, muy cómodo el lugar."
The price is €36
includes taxes & fees
27 Jan - 28 Jan
Hotel G
Swissôtel Santa Cruz De La Sierra
Massages

Swissôtel Santa Cruz De La Sierra

4.5 star property
9.2 out of 10, Wonderful, (73)
"Great location and excellent facilities in Santa Cruz de la Sierra. The professionalism and customer service of the staff are outstanding. The bar could offer a wider variety of spirits, but overall, my stay was very good. Highly recommended! "
The price is €85
includes taxes & fees
6 Feb - 7 Feb
Swissôtel Santa Cruz De La Sierra
Delfines Collection Hotel By Mercure
Room

Delfines Collection Hotel By Mercure

3.5 star property
8.8 out of 10, Excellent, (47)
"Pieza grande, cama muy confortable. Muy bien ubicada, desayuno variado. Buena piscina, el gimnasio muy pequeño "
Delfines Collection Hotel By Mercure
Novotel Santa Cruz De La Sierra
Lobby sitting area

Novotel Santa Cruz De La Sierra

5.0 star property
9.2 out of 10, Wonderful, (83)
"Great hotel and location also very nice staff."
The price is €87
includes taxes & fees
5 Feb - 6 Feb
Novotel Santa Cruz De La Sierra
Hotel LP Santa Cruz Centro
Standard Room, 2 Single Beds

Hotel LP Santa Cruz Centro

3.0 star property
7.8 out of 10, Good, (277)
"Clean, friendly staff"
The price is €57
includes taxes & fees
29 Jan - 30 Jan
Hotel LP Santa Cruz Centro
Hotel Cortez
Exterior

Hotel Cortez

3.5 star property
9.0 out of 10, Wonderful, (92)
"Beautiful and the staff was incrediblly efficient and kind."
The price is €97
includes taxes & fees
24 Jan - 25 Jan
Hotel Cortez
HOTEL OSHO
Reception

HOTEL OSHO

3.5 star property
9.0 out of 10, Wonderful, (23)
"I like his service "
The price is €78
includes taxes & fees
29 Jan - 30 Jan
HOTEL OSHO
Senses Centro
Outdoor pool

Senses Centro

3.5 star property
7.4 out of 10, Good, (94)
"We ended up accident at the sister hotel, Senses boutique because this website had that hotels address on the app. An oops for you, but it worked out for use due to the excellent location, and the ability to check in a few hours earlier than policy."
Senses Centro
Chairú Eco Hotel
Front of property

Chairú Eco Hotel

3.5 star property
9.6 out of 10, Exceptional, (30)
"The staff was extremely helpful. Due to our flight schedule we arrived 6 hours prior to check-in. Once a room became available that morning after a guest checked out, they got it cleaned immediately and got us in several hours before our actual check in. We were extremely grateful for their kindness. "
The price is €48
includes taxes & fees
28 Jan - 29 Jan
Chairú Eco Hotel
Hostal Killa
Terrace/patio

Hostal Killa

3.0 star property
The price is €24
includes taxes & fees
26 Jan - 27 Jan
Hostal Killa
Apart Hotel Buen Retiro
Courtyard

Apart Hotel Buen Retiro

3.0 star property
8.8 out of 10, Excellent, (56)
"Overall, a pleasant stay. The hotel was centric and walkable to the city's center. The amenities and rooms were adequately stocked and the staff was friendly and helpful. Uber is an economic and accessible option to explore the rest of the city. "
Apart Hotel Buen Retiro
Alfonsina Hotel Boutique by Inboccaluppo
Outdoor pool

Alfonsina Hotel Boutique by Inboccaluppo

3.5 star property
9.6 out of 10, Exceptional, (31)
"A super friendly boutique hotel. Room was spacious, well equipped and chic. Bed super comfortable and shower was great. Lovely breakfast with made to order eggs."
The price is €99
includes taxes & fees
4 Feb - 5 Feb
Alfonsina Hotel Boutique by Inboccaluppo
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santa Cruz.
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
The price is €100 per night from 25 Jan to 26 Jan
€100
includes taxes & fees
25 Jan - 26 Jan
8.8/10 Excellent! (173 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 4-star hotels in Santa Cruz?
If you’re seeking luxury comfort and loads of amenities during your Santa Cruz retreat, consider TRYP by Wyndham Santa Cruz. This 4-star hotel offers a spa tub and a terrace. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia also gets stellar reviews from Expedia guests. Concierge services and a garden are among its conveniences.
How much does it cost to stay in a 4-star hotel in Santa Cruz?
Expedia can help you easily locate the perfect 4-star hotel for your holiday in Santa Cruz. Use our filter tool to tailor your search by things like price, conveniences and star rating and get access to terrific deals in a few clicks.

  • Search for the lowest price from €87

What's the difference between 5-star and 4-star hotels in Santa Cruz?
If you choose to spend your holiday at a 4-star hotel in Santa Cruz, you’ll typically find plenty of conveniences to ensure you’re comfortable, such as a restaurant, gym and pool. You can enjoy top-quality service and deluxe accommodation. Choose a 5-star hotel and you’ll get a few extra perks — think concierge assistance, on-site spas and opulent turndown services. You’re likely to get more amenities and premium services at a 5-star stay, but both are fabulous options for luxury travellers.
Does Santa Cruz have any 4-star all-inclusive resorts?
Search for a 4-star all-inclusive resort in Santa Cruz by using Expedia’s convenient filters. If none are available, we have a number of other options in this city that make the perfect base for your adventure. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia and TRYP by Wyndham Santa Cruz are both rated 4 stars and provide an excellent balance between amenities, comfort and affordability.
Are there any 4-star casino hotels in Santa Cruz?
To find what you’re looking for in Santa Cruz, use our handy filter tool to narrow down your search. With resort-style amenities and a level of service that’s hard to beat, our 4-star casino hotels are a safe bet for a good time.
What are the top 4-star hotels in downtown Santa Cruz?
Located about 5 kilometres northwest from downtown Santa Cruz, TRYP by Wyndham Santa Cruz will place you right in the action. This 4-star hotel also has a swimming pool and a terrace for your convenience.