Compare Car Hire in Panama

Search and Compare from Car Companies in Panama

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

Members save 10% more on select hotels, cars, activities and holiday rentals. Sign up.Opens in a new window

Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

Top Cars Deal in Panama

* Price found within the past 60 days. Click for updated prices.

Don't see what you're looking for?

See all car hire in Panama
View all cars

Frequently asked questions

Can I rent a car from Fort Smith Regional Airport (FSM)?
Touch down at Fort Smith Regional Airport (FSM) and then head to Enterprise or Hertz, a short commute away. You’ll be exploring the sights and sounds of Panama in your own set of wheels in no time.
What happens if I need to cancel my Panama car reservation?
That won’t be a problem. If you can cancel your prepaid reservation at least six hours prior to the scheduled collection time, you may be eligible for a full refund. Be sure to read your rental policy as there are some exemptions. Click through to our Customer Service Portal if you still have queries.
Why should I rent a Panama car with Expedia?
With car rental companies to pick from in Panama, Expedia makes it easy to find a set of wheels that suits your style. And when you combine your rental vehicle, hotel and flights into a package, you can save even more on your entire Panama vacation. From affordable economy models to full-size SUVs and more, Expedia will get you on the road to your next amazing adventure.
How do I find the best car rental deals in Panama with Expedia?
Score an amazing deal with Expedia. All you have to do is choose your car type, select your dates and pickup and drop-off locations, and compare offers from all the big-name brands. Make even bigger savings when you combine your Panama car rental with flight or hotel bookings.
What do you need to rent a car in Panama?
Before you can hit the road in Panama, you’ll need a valid driver’s license and a credit card in the same name. If you choose not to take out the company’s insurance plan, you may also have to provide proof of other coverage. Rules can vary, so read the policy terms and conditions before you choose a rental supplier.
Can I rent a car for a month or longer in Panama?
Click through to our long-term car rental deals page, enter your preferences and then choose a ride that suits. Whether you’re basing yourself in Panama or venturing beyond, Expedia will help you find a long-term rental at an awesome rate.
Where can I find a Panama car rental if I am younger than 25?
If you’re a young driver looking for a car rental in Panama, check the policies of the various car rental companies you’re interested in. Some may rent to drivers under the age of 25, some may not. There may be extra costs if you’re between 21 and 24 years old. To escape any surprise fees and charges on pickup, make sure you know what to expect.