Downtown South San Francisco Holidays

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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown South San Francisco
Union Square featuring a skyscraper and a city

Union Square

4/5(287 area reviews)

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Find hotels in Union Square

Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport N
3 out of 5
20 Airport Blvd, South San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is €105 per night from 22 Jun to 23 Jun
€105
22 Jun - 23 Jun
includes taxes & fees
8/10 Very Good! (2,020 reviews)
"Very pleased with our stay. Room was very clean and updated. We were staying for a quick overnight before flying home from vacation so we were not able to use the pool. Would 100% stay again."

Reviewed on 10 Jun 2025

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hyatt Regency San Francisco
Hyatt Regency San Francisco
4 out of 5
5 Embarcadero Center, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is €232 per night from 16 Jun to 17 Jun
€232
16 Jun - 17 Jun
includes taxes & fees
9.2/10 Wonderful! (1,687 reviews)
"Clean, up to date and great services"

Reviewed on 10 Jun 2025

Hyatt Regency San Francisco
Holiday Inn Golden Gateway by IHG
Holiday Inn Golden Gateway by IHG
3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is €134 per night from 15 Jun to 16 Jun
€134
15 Jun - 16 Jun
includes taxes & fees
8.8/10 Excellent! (4,085 reviews)
"Great hotel, good location Clean rooms, no noise from the streets"

Reviewed on 14 Jun 2025

Holiday Inn Golden Gateway by IHG
See all 4,703 properties in Downtown South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Downtown South San Francisco holiday package cost?
From just . Yes, you read that right. Our Downtown South San Francisco holiday packages are a simple way to make your dollar go further. Combine your favourite hotels, flights and car rentals and get to know this popular destination.
How do I get a cheap travel package to Downtown South San Francisco?
Bundle your bookings with Expedia to save on your next big adventure. With more than 550 airlines and 1,000,000 properties globally, your Downtown South San Francisco holiday package can be tailored exactly to suit your travel style. With all those extra dollars, why not add one or two interesting tours and activities? It’s an easy way to unlock even more bargains. That dream holiday to Downtown South San Francisco is much closer than you thought!
Where should I stay in Downtown South San Francisco?
A trip to Downtown South San Francisco wouldn’t be complete without seeing South San Francisco Convention Centre, Sees Candies and K1 Speed San Francisco. Spend your nights close to these top attractions and make sightseeing easy.
What are the top hotels in Downtown South San Francisco?
Book a stay at Airport Inn. It’s one of this area’s most sought-after hotels. Another well-known option in Downtown South San Francisco is Rustic/modern Design, Oasis City Getaway.
How far in advance should I book my Downtown South San Francisco holiday?
Travellers are generally able to look up international airfares on Expedia up to a year in advance of departure. Booking at the last minute? With a stroke of luck, it’s still possible to purchase a cheaper ticket only weeks before your journey.
What does an Expedia Downtown South San Francisco travel package include?
With Expedia, you can choose a combination of hotels, flights and car rentals to build your perfect Downtown South San Francisco travel package. Once you’ve made your booking, you can add on all the fun stuff like activities and tours. Don’t forget, the more you bundle, the more cash you’ll save!
What should I know before booking a Downtown South San Francisco travel package?
When you book your hotels, flights and car rentals together, you’ll land great discounts. Whether you’re organising an outdoor getaway in a chalet or prefer to stay in a ritzy city hotel, Expedia can help make it happen.
Can I choose my airline with a Downtown South San Francisco Expedia holiday package?
Definitely. Expedia has more than 550 airline partners to select from all over the world. With all that choice, finding the ideal carrier to whisk you away to Downtown South San Francisco will be a cinch.
If I'm not able to travel, can I cancel my Downtown South San Francisco holiday package?
It’s impossible to predict what tomorrow might bring, so it’s comforting to know that you can change or cancel your Downtown South San Francisco holiday package. If you booked in the last 24 hours, you may be entitled to a refund. If it’s an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Popular places to visit

Oracle Park

Oracle Park

4.5/5(24 reviews)

Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.

Oracle Park
Golden Gate Bridge which includes a suspension bridge or treetop walkway, night scenes and a bay or harbour

Golden Gate Bridge

4.5/5(362 reviews)

Walk across one of the most photogenic bridges in the world for unrivalled views from both sides.

Golden Gate Bridge
Pier 39 showing street scenes, signage and a city

Pier 39

4/5(364 reviews)

Sea lions are the star attraction at one of the liveliest piers on San Francisco’s historic waterfront.

Pier 39

Things to do

Golden Gate Bridge at night

San Francisco Night Tour

€47
per adult
76% of travellers recommend
San Francisco Night Tour
San Francisco: Flyer Theater, 7D Ride & Laser Maze Combo

San Francisco: Flyer Theater, 7D Ride & Laser Maze Combo

€25
per adult
100% of travellers recommend
San Francisco: Flyer Theater, 7D Ride & Laser Maze Combo
San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat

San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat

€33
per adult
94% of travellers recommend
San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.