Photo by Delen Wong

Isla Santa María Hotels

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Isla Santa María hotels

Our top choices for Isla Santa María hotels

Hotel el descanso del Guia

3.5 star property
8.8 out of 10, Excellent, (166)
"Beautiful and spacious family room. Good breakfast and the staff is courteous. I highly recommend this hotel. "
Hotel el descanso del Guia

Hotel Fiesta

3.5 star property
9.0 out of 10, Wonderful, (364)
"Very nice place and the very large hot tub was nice to relax in after the day."
The price is €133
6 Sept - 7 Sept
Hotel Fiesta

Fernandina Hotel & Spa Galápagos

3.0 star property
9.2 out of 10, Wonderful, (17)
"Great service awesome hotel and beautiful island "
Fernandina Hotel & Spa Galápagos

Galapagos Dreams

3.0 star property
8.8 out of 10, Excellent, (122)
"The whole team did an amazing job, and special shout out to Andy who went above and beyond to provide the best service. Jonatan has an incredible team and they made this one of the best experiences even when things did not go as planned. They were able to accommodate as much as possible in a short period of time. Hotel and tour agency staff are top notch."
The price is €78
6 Sept - 7 Sept
Galapagos Dreams

Posada del Mar

3.0 star property
9.8 out of 10, Exceptional, (196)
"Great value for location."
The price is €60
4 Sept - 5 Sept
Posada del Mar

Hotel Ninfa

3.5 star property
8.4 out of 10, Very good, (209)
"Great hotel to use as your base while exploring Galapagos, and a lovely pool, hot tub and bar to come home to at the end of the day"
Hotel Ninfa

Angermeyer Waterfront Inn

3.5 star property
9.4 out of 10, Exceptional, (121)
"Beautiful view and very friendly staff. You do have to take a water taxi ($1 and operates 24/7) to the main part of downtown Santa Cruz but the view is worth it! Also it’s across from The Point by Midoro which as an amazing view and food. I would stay there again! "
The price is €246
9 Sept - 10 Sept
Angermeyer Waterfront Inn

Hotel Cucuve

4.0 star property
10.0 out of 10, Exceptional, (257)
"Very nice location, friendly staff "
The price is €187
5 Sept - 6 Sept
Hotel Cucuve

Hostal Sir Francis Drake

2.5 star property
7.6 out of 10, Good, (71)
"Great location!"
Hostal Sir Francis Drake

Twin Hotel Galapagos

3.0 star property
8.4 out of 10, Very good, (42)
"This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast."
The price is €83
15 Sept - 16 Sept
Twin Hotel Galapagos

Hotel La Isla

3.5 star property
9.6 out of 10, Exceptional, (61)
"We are so happy we chose to stay here while on the island. Great location, staff, and property! "
Hotel La Isla

White House Galapagos

2.5 star property
9.0 out of 10, Wonderful, (95)
"Better than I expected. Great value "
White House Galapagos

Hotel La Casa de Judy

3.0 star property
9.0 out of 10, Wonderful, (157)
"The staff was nice and friendly. They were accommodating to our needs. They offered helpful suggestions to places and food locations nearby. Recommend coming here again."
The price is €78
5 Sept - 6 Sept
Hotel La Casa de Judy

Hotel Coloma Galapagos

3.0 star property
9.4 out of 10, Exceptional, (184)
"The staff was very friendly, and the hotel is very close to everything. "
Hotel Coloma Galapagos

Hotel Santa Fe

4.0 star property
9.6 out of 10, Exceptional, (14)
"Beautiful hotel, with amazing staff, and great location "
The price is €175
4 Sept - 5 Sept
Hotel Santa Fe

Blu Galapagos Sustainable Waterfront Lodge

4.0 star property
8.8 out of 10, Excellent, (115)
"We had a great stay at Blu Galapagos. Loved the location and our room was perfect - Great view, well maintained and had a king bed. Even if the description says queen bed and the picture looks like a king, you can trust the picture. Morning breakfast with iguanas and seals, and all day Galapagos coffee availability made this stay special. "
The price is €156
7 Sept - 8 Sept
Blu Galapagos Sustainable Waterfront Lodge

Maidith Galapagos Inn

3.0 star property
10.0 out of 10, Exceptional, (95)
"We loved our stay! The staff was very helpful and the room was spacious and such a unique design. We would highly recommend!"
The price is €108
5 Sept - 6 Sept
Maidith Galapagos Inn

Casa del Lago Lodging House

2.0 star property
7.8 out of 10, Good, (13)
"The Tortuga bay suite is right by the street so you hear the street noise until about 10:30pm on workdays and about 11:30pm on a Friday. The air conditioner doesn’t work well. It makes a noise at night and is quite disturbing. With the many mosquitoes, we could not open the windows and it was quite a terrible experience to sleep at night. The soap and shampoo/body wash are diluted. The fridge is incredibly noisy and you cannot sleep with it being on. The plates are dirty and require extra...
Casa del Lago Lodging House

Plaza Luna Suites

3.0 star property
9.8 out of 10, Exceptional, (27)
"This hotel great location and employees are awesome, wonderful, nice and very professional friendly. This hotel is a gem in Puerto Ayora "
Plaza Luna Suites

Grand Hotel Leon Marino Galapagos

3.0 star property
8.6 out of 10, Excellent, (11)
"Staff was very friendly and location convenient. Modern interior."
The price is €76
4 Oct - 5 Oct
Grand Hotel Leon Marino Galapagos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Near an Attraction

Post Office Bay
Post Office Bay

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.

Learn more about Isla Santa María

Explore attractions like Galápagos National Park and Post Office Bay as you discover things to see and do in Isla Santa María.

Top Isla Santa María Hotel Reviews

More cheap stays in Isla Santa María

More cheap stays in Isla Santa María

Frequently asked questions

Where is the best place for a stay in Isla Santa María?

Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Hotel el descanso del Guia and Hotel Cucuve. See all available top hotels, or vacation rentals in Isla Santa María.

What are some of the best holiday rentals that Isla Santa María has to offer?

Villa Galapagos: This holiday home rental outside of Isla Santa María is located near the beach, and offers a private garden, air conditioning and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Isla Santa María.

If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.

What is staying in Isla Santa María like?

Travellers to Isla Santa María will find plenty to explore and enjoy. There are 197 hotels and other accommodation options in the larger region. Find out more about Isla Santa María.

What is there to see in Isla Santa María?

Favourite places to visit include Galápagos National Park, Post Office Bay and Punta Suarez. Take a look at what more there is to see and do in Expedia's Isla Santa María guide.

What's the seasonal weather in Isla Santa María?

The hottest months are usually March and February, with an average temperature of 26°C, while the coldest months are September and October, with an average of 22°C. Average annual precipitation for Isla Santa María is 319 mm.