Hyannis Hotel Guide - Main Street Hyannis hotels in Hyannis, United States of America.

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top Trending Hotels Near Main Street Hyannis

Hyannis Travel Inn

2.5 star property
9.6 out of 10, Exceptional, (1006)
"Enjoyed our stay will come back again "
The price is €167
includes taxes & fees
4 Aug - 5 Aug
Hyannis Travel Inn

Anchor In Distinctive Waterfront Lodging

3.0 star property
9.4 out of 10, Exceptional, (1002)
"This is a quaint, smaller hotel, overlooking the wharf of Hyannis "
The price is €356
includes taxes & fees
6 Aug - 7 Aug
Anchor In Distinctive Waterfront Lodging

Cape Cod Harbor House Inn

2.5 star property
9.2 out of 10, Wonderful, (270)
"Literally across the street from several restaurants, bars, and ferries. Great location. Spanky’s had the best lobster bisque and blackened cod. "
The price is €185
includes taxes & fees
23 Jul - 24 Jul
Cape Cod Harbor House Inn

SeaCoast Inn

2.0 star property
9.0 out of 10, Wonderful, (652)
"Spacious room, convenient location, nice to have kitchenette. "
The price is €175
includes taxes & fees
3 Aug - 4 Aug
SeaCoast Inn

Cape Cod Inn

2.0 star property
8.8 out of 10, Excellent, (447)
"Place was right in the center of Hyannis, room and bathroom were clean. We enjoyed our stay"
The price is €129
includes taxes & fees
5 Aug - 6 Aug
Cape Cod Inn

Hyannis Inn

2.0 star property
8.6 out of 10, Excellent, (1010)
"Clean and convenient to downtown and the ferry. "
Hyannis Inn

Uncommoner Hotel by Reverie Boutique Collection

3.0 star property
9.2 out of 10, Wonderful, (5)
"This place is a gem! I throughly enjoyed myself for their opening weekend. The owner P was amazing! Very hospitable and gracious. The property has two pools that are as deep as 9ft and as shallow as 3ft.The rooms are themed and decorated immaculately. A great stay all together."
The price is €255
includes taxes & fees
23 Jul - 24 Jul
Uncommoner Hotel by Reverie Boutique Collection

Hampton Inn & Suites Cape Cod-West Yarmouth

2.5 star property
8.8 out of 10, Excellent, (1005)
"Our stay was great1 rooms were clean and the staff very accomodating. Close to restaurants and beaches."
The price is €238
includes taxes & fees
20 Aug - 21 Aug
Hampton Inn & Suites Cape Cod-West Yarmouth

Bayside Resort Hotel

3.0 star property
8.8 out of 10, Excellent, (1411)
"great stay"
Bayside Resort Hotel

Cape Sands Inn

2.5 star property
8.4 out of 10, Very good, (1013)
"Great stay."
The price is €107
includes taxes & fees
27 Jul - 28 Jul
Cape Sands Inn

Doubletree by Hilton Cape Cod - Hyannis

4.0 star property
8.4 out of 10, Very good, (839)
"Nice place to stay "
The price is €259
includes taxes & fees
17 Aug - 18 Aug
Doubletree by Hilton Cape Cod - Hyannis

Comfort Inn Hyannis - Cape Cod

2.5 star property
7.8 out of 10, Good, (1013)
"Clean and great location "
The price is €134
includes taxes & fees
3 Aug - 4 Aug
Comfort Inn Hyannis - Cape Cod

Hyannis Harbor Hotel

3.5 star property
8.0 out of 10, Very good, (1003)
"Great place. I recommend this stay to several friends and groups"
The price is €321
includes taxes & fees
27 Jul - 28 Jul
Hyannis Harbor Hotel

Americas Best Value Inn & Suites Hyannis Cape Cod

2.0 star property
7.6 out of 10, Good, (1006)
"We liked that there was an indoor and outdoor pool staff was very nice room was nice and clean "
The price is €116
includes taxes & fees
3 Aug - 4 Aug
Americas Best Value Inn & Suites Hyannis Cape Cod

Windrift Motel

2.0 star property
8.0 out of 10, Very good, (220)
"It was quiet and spacious and clean Would recommend!"
The price is €152
includes taxes & fees
13 Aug - 14 Aug
Windrift Motel

Heritage House Inn on Cape Cod

2.5 star property
7.4 out of 10, Good, (116)
"The location was very good. very close to the main street, beach is around 5 mins drive. we will definitely come back and stay with them again. "
The price is €77
includes taxes & fees
19 Aug - 20 Aug
Heritage House Inn on Cape Cod

Holiday Inn Hyannis by IHG

3.0 star property
8.2 out of 10, Very good, (899)
"Nice room with good location, friendly staff"
The price is €244
includes taxes & fees
27 Jul - 28 Jul
Holiday Inn Hyannis by IHG

Hyannis Host Inn

2.0 star property
7.8 out of 10, Good, (414)
"Easiest check-in I've ever had! Hosts were kind, quick, and provided what was requested. Excellent experience."
The price is €132
includes taxes & fees
27 Jul - 28 Jul
Hyannis Host Inn

Sunbird ANNEX Resort

2.0 star property
7.8 out of 10, Good, (743)
"Staff was great very helpful, and it is family friendly. "
The price is €157
includes taxes & fees
28 Jul - 29 Jul
Sunbird ANNEX Resort

Sunbird Cape Cod Resort

2.5 star property
7.6 out of 10, Good, (410)
"Was close to everything, staff was extremely friendly and nice. "
The price is €173
includes taxes & fees
27 Jul - 28 Jul
Sunbird Cape Cod Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Main Street Hyannis Hotel Reviews

Destinations near Hyannis

St. Francis Xavier Church
St. Francis Xavier Church

St. Francis Xavier Church

Learn about the local history of Hyannis with a stop at St. Francis Xavier Church. Amble around this family-friendly area's beautiful beaches and enjoy its seafood restaurants.

Frequently asked questions

What's the area like around Main Street Hyannis?

Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 184 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Main Street Hyannis?

Adjacent to Main Street Hyannis, Americas Best Value Inn & Suites Hyannis Cape Cod is one of the top choices for your stay based on our traveller data, and this hotel offers an indoor pool and free parking. Other good options within a short distance include Hyannis Harbor Hotel and Hyannis Inn.

How many hotels can I expect to find near Main Street Hyannis?

Expedia has 184 hotels and other accommodation options within a mile from Main Street Hyannis.

If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?

Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.

What can I see and do near Main Street Hyannis?

John F. Kennedy Hyannis Museum, Cape Cod Maritime Museum and Whydah Pirate Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and Sandy Neck Lighthouse are landmarks that you won't want to miss. You can enjoy live performances at Cape Cod Melody Tent and Barnstable Performing Arts Center.