O Brien Hotels

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Our top choices for O Brien hotels

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
8.0 out of 10, Very good, (120 reviews)
"Dog friendly and price."
United States
John
The price is €66
includes taxes & fees
16 Mar - 17 Mar
Motel 6 – Lake City, Fl – Medical Center

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.0 out of 10, Good, (534 reviews)
"Clean spacious rooms, friendly staff, convenient location "
United States
Jerry
The price is €87
includes taxes & fees
8 Apr - 9 Apr
Quality Inn & Suites Live Oak I-10 Exit 283

Royal Inn

Royal Inn
2.0 star property
Live Oak
6.2 out of 10, (47 reviews)
"Good for the price "
United States
Jaiden
Royal Inn

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (644 reviews)
"Clean room. Staff very friendly. Stay ok for the price. "
United States
Janet
The price is €66
includes taxes & fees
29 Mar - 30 Mar
Quality Inn White Springs Suwanee

Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (285 reviews)
"Clean room with plenty of towels and soaps. "
United States
Melissa
The price is €63
includes taxes & fees
14 Apr - 15 Apr
Econo Lodge Live Oak

High Springs Country Inn

High Springs Country Inn
2.0 star property
High Springs
8.4 out of 10, Very good, (23 reviews)
"Great value! Friendly staff. Parking easy. "
United States
Brandon
The price is €77
includes taxes & fees
17 Mar - 18 Mar
High Springs Country Inn

Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very good, (807 reviews)
"Everything was excellent in all phases"
United States
Tyrone
The price is €122
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express & Suites Live Oak by IHG

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (419 reviews)
"It was a good, basic room with everything I needed. Very spacious. "
United States
Douglas
The price is €81
includes taxes & fees
16 Mar - 17 Mar
BlueGem Motel

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (187 reviews)
"Room was spotless, property was nicely groomed, snacks, coffee and water was provided overall great trip."
United States
Ashley
The price is €183
includes taxes & fees
29 Mar - 30 Mar
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (130 reviews)
"Easy parking. Friendly staff. We extended our stay and had to switch rooms. The 1st kingsize bad was great. But when we changed rooms the queen size bed sagged in the middle."
United States
MARGARET
Cindys Motel

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.8 out of 10, Excellent, (24 reviews)
"Awesome place to stay, beautiful location and great accommodations. Friendly staff and lots to do!"
United States
Lauren
The price is €38
includes taxes & fees
17 Mar - 18 Mar
Suwannee River Rendezvous

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (490 reviews)
"Breakfast awesome Parking great Staff awesome "
United States
Bryan
The price is €112
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites Alachua I-75

Americas Best Value Inn Alachua

Americas Best Value Inn Alachua
2.0 star property
Alachua
4.8 out of 10, (614 reviews)
"Great staff "
United States
Sion
The price is €71
includes taxes & fees
16 Mar - 17 Mar
Americas Best Value Inn Alachua

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (595 reviews)
"Everything always great"
United States
Michelle
The price is €64
includes taxes & fees
16 Mar - 17 Mar
Palms Garden Inn

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.6 out of 10, Exceptional, (1,005 reviews)
"Clean room and facilities with very friendly staff during our entire stay."
United States
Moriah
The price is €110
includes taxes & fees
5 Apr - 6 Apr
Comfort Suites Lake City

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,001 reviews)
"Quick service and clean rooms"
United States
Lexus
The price is €132
includes taxes & fees
13 Apr - 14 Apr
Holiday Inn & Suites Lake City by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean hotel and friendly staff"
United States
Joseph
The price is €111
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (772 reviews)
"Very clean property, staff was always helpful and kind. "
United States
Tosha
The price is €127
includes taxes & fees
5 Apr - 6 Apr
Home2 Suites by Hilton Lake City

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,003 reviews)
"Nice stay"
United States
Timothy
The price is €129
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites Lake City

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (210 reviews)
"Great hotel "
United States
Guillermo
The price is €100
includes taxes & fees
22 Mar - 23 Mar
Fairfield Inn & Suites Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

More cheap stays in O Brien

Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are La Quinta Inn & Suite by Wyndham Lake City and Best Western Plus Lake City. See all available top hotels, or vacation rentals in O Brien.
What are some of the best holiday rentals that O Brien has to offer?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: This highly rated holiday home rental in O Brien is located on the beach, and has a balcony, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Offers buffet, an outdoor pool and complimentary high-speed (wired) Internet access. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and La Quinta Inn & Suite by Wyndham Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Bob's River Place in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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