San Cosme y Damian Hotels

Yes! Most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in San Cosme y Damian.

Visitors can enjoy all that San Cosme y Damian has to offer, including its museums. You'll find 18 Expedia hotels and other accommodation options in the larger area of Encarnacion.

A couple of favourite places to visit are Buenaventura Suarez Planetarium and Guarani Jesuit Ruins of San Cosme and San Damián. Take a look at what more there is to see and do in Expedia's San Cosme y Damian guide.

The hottest months are usually January and February, with an average temperature of 26°C, while the coldest months are July and June, with an average of 17°C. The rainiest months in San Cosme y Damian are October, November, May and April, with each month seeing an average of 198 mm of rainfall.