Santa Cruz Hotels

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Santa Cruz hotels

Hotel Finca Las Hortensias

3.0 star property
8.2 out of 10, Very good, (166)
"Front desk service was excellent, the food was delicious and the service from Saul was wonderful. "
The price is €61
includes taxes & fees
2 Mar - 3 Mar
Hotel Finca Las Hortensias

Villa Granada

2.0 star property
9.2 out of 10, Wonderful, (37)
"Very noisy "
The price is €40
includes taxes & fees
10 Mar - 11 Mar
Villa Granada

Verticca Hotel

3.0 star property
9.6 out of 10, Exceptional, (111)
"Excelente servicio de día y noche. Súper amables y limpio "
The price is €150
includes taxes & fees
5 Mar - 6 Mar
Verticca Hotel

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

3.5 star property
9.4 out of 10, Exceptional, (574)
"Nothing to do around the hotel"
The price is €120
includes taxes & fees
7 Mar - 8 Mar
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Fiesta Inn Ecatepec

3.5 star property
8.8 out of 10, Excellent, (659)
"Thank you. "
The price is €86
includes taxes & fees
28 Feb - 1 Mar
Fiesta Inn Ecatepec

Hotel Vía la Villa

2.5 star property
7.8 out of 10, Good, (295)
"This is a hidden gem. Low price, cleanliness, modern, good staff, what more can you ask for. I've stayed at this hotel 2 times now and it has been great. I didn't expect anything luxurious but what I did expect was a clean and convenient option and they exceeded. Thank you so much for your service."
The price is €41
includes taxes & fees
10 Mar - 11 Mar
Hotel Vía la Villa

City Express by Marriott Ciudad de México La Villa

3.0 star property
8.8 out of 10, Excellent, (841)
"The staff were very good, breakfast was so so, next to a big grocery store chain. Walkable to Our Lady of Guadalupe Shrine. Less than $10 for uber from airport. Big room, clean. "
The price is €68
includes taxes & fees
3 Mar - 4 Mar
City Express by Marriott Ciudad de México La Villa

Gran Hotel Villa de Madrid

3.5 star property
8.0 out of 10, Very good, (322)
"It was a big space and was convenient to the basilica "
The price is €56
includes taxes & fees
25 Feb - 26 Feb
Gran Hotel Villa de Madrid

Hotel Piet

2.0 star property
7.0 out of 10, Good, (71)
"The property is an 'hourly, adult-only' hotel. It is Ok for solo traveller like myself. The property is old and not well kept but is one of the cheapest accomodations I could find. The property is kept to the best possible standards by the staff who are very engaged and polite. Antonio and Valentina are the names of the staff who try to accommodate your needs but the hotel is in a normal, poorer part of the city and dining options around are limited but available. However, if your aim is to just...
The price is €16
includes taxes & fees
25 Feb - 26 Feb
Hotel Piet

Gran Hotel Panorama

3.0 star property
8.2 out of 10, Very good, (859)
"Decent hotel for the price. Not in the safest area but as long as you just take an Uber or taxi to get to your destination: you will be fine. No A/C but hotel and room was not hot. Hotel does provide a fan. "
The price is €22
includes taxes & fees
25 Feb - 26 Feb
Gran Hotel Panorama

Holiday Inn Express Mexico Basilica by IHG

3.0 star property
9.2 out of 10, Wonderful, (1003)
"I loved my stay here. Super clean and friendly."
The price is €71
includes taxes & fees
4 Mar - 5 Mar
Holiday Inn Express Mexico Basilica by IHG

Hotel Brasilia

3.0 star property
9.0 out of 10, Wonderful, (1004)
"People were very courteous and respectful, rooms very neat and clean "
The price is €57
includes taxes & fees
27 Feb - 28 Feb
Hotel Brasilia

Mala Vecindad Centro Historico

3.0 star property
8.6 out of 10, Excellent, (48)
"Good "
The price is €55
includes taxes & fees
27 Feb - 28 Feb
Mala Vecindad Centro Historico

Hotel MX lagunilla

3.5 star property
8.2 out of 10, Very good, (347)
"Muy buen lugar, amplias habitaciones y tiene estacionamiento. Incluye desayuno y el personal es muy atento. El entorno no es el más bonito, pero hay que andar con cuidado."
The price is €39
includes taxes & fees
24 Mar - 25 Mar
Hotel MX lagunilla

City Express by Marriott Ciudad De México La Raza

3.0 star property
8.8 out of 10, Excellent, (855)
"Clean hotel"
The price is €76
includes taxes & fees
28 Feb - 1 Mar
City Express by Marriott Ciudad De México La Raza

Kali La Raza Mexico City

2.5 star property
9.8 out of 10, Exceptional, (10)
"Buen lugar para quedarte, muy comodo y tranquilo."
The price is €58
includes taxes & fees
25 Feb - 26 Feb
Kali La Raza Mexico City

Downtown Treasure Place

2.5 star property
8.8 out of 10, Excellent, (513)
"Really nice and calm place to sleep "
The price is €30
includes taxes & fees
25 Feb - 26 Feb
Downtown Treasure Place

One Ciudad de Mexico La Raza

3.0 star property
8.6 out of 10, Excellent, (740)
"Manchas en la alfombra y la comida no fue tan rica"
The price is €71
includes taxes & fees
25 Feb - 26 Feb
One Ciudad de Mexico La Raza

Hotel Dharma

3.0 star property
8.0 out of 10, Very good, (342)
"Staff friendly and place clean and quiet."
The price is €34
includes taxes & fees
25 Feb - 26 Feb
Hotel Dharma

Hotel Lepanto Reforma

3.0 star property
8.4 out of 10, Very good, (541)
"Nos encantó hospedarnos aquí el personal es lo máximo super recomendado y nos volveremos a quedar aquí "
The price is €62
includes taxes & fees
17 Mar - 18 Mar
Hotel Lepanto Reforma
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santa Cruz
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Santa Cruz

Check out Hacienda La Concepcion and National Museum of the Viceroyalty—just a couple of the sights around Santa Cruz.

Frequently asked questions

Where is the best place for a stay in Santa Cruz?

Located 18.9 mi (30.4 km) from the heart of Santa Cruz, InterContinental Presidente Mexico City by IHG is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Hyatt Regency Mexico City and Hotel Polanco. See all available top hotels, or vacation rentals in Santa Cruz.

What are some of the best holiday rentals that Santa Cruz has to offer?

322PH HighEnd City View Penthouse Sleeps 8 Polanco: This holiday home rental outside of Santa Cruz has laundry facilities and WiFi to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

What are some accommodation options with pools in Santa Cruz?

Hotel Finca Las Hortensias: Features free self-parking, an outdoor pool and free WiFi. Hyatt Regency Mexico City and Fiesta Americana México Toreo are a couple of other choices that offer an on-site pool. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Hotel Finca Las Hortensias is a top spa hotel featuring a restaurant and a bar.

What is staying in Santa Cruz like?

Those travelling to Santa Cruz will definitely enjoy the sights to see and things to do. There are 1636 hotels and other accommodation options in the surrounding area. Find out more about Santa Cruz.

What are the top places to visit in Santa Cruz?

Places to visit in the wider area include Hacienda La Concepcion, National Museum of the Viceroyalty and San Marcos Power Center. You'll also find Xochitla Ecological Park and Arcos del Sitio in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.

What's the seasonal weather like in Santa Cruz?

The hottest months are usually April and May, with an average temperature of 18°C, while the coldest months are January and December, with an average of 14°C. The rainiest months in Santa Cruz are August, July, September and June, with each month seeing an average of 186 mm of rainfall.