Santa Fe Hotels

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Santa Fe hotels

Best Western Waldo Inn and Suites

2.5 star property
8.8 out of 10, Excellent, (846)
"Enjoyed the comfort of the room, bed/pillows; the shower was great with good water pressure and breakfast was good. Thank you. "
The price is €110
includes taxes & fees
27 Feb - 28 Feb
Best Western Waldo Inn and Suites

Camellia Rose Inn

3.0 star property
9.8 out of 10, Exceptional, (201)
"Beautiful stay "
The price is €278
includes taxes & fees
20 Feb - 21 Feb
Camellia Rose Inn

Sweetwater Branch Inn

3.5 star property
9.6 out of 10, Exceptional, (859)
" Wonderful atmosphere absolutely delightful and would definitely recommend and would definitely return"
The price is €153
includes taxes & fees
25 Feb - 26 Feb
Sweetwater Branch Inn

Depot Village

2.0 star property
9.4 out of 10, Exceptional, (23)
"This was a unique place to stay "
The price is €120
includes taxes & fees
23 Feb - 24 Feb
Depot Village

Hampton Inn & Suites Gainesville-Downtown

3.0 star property
8.6 out of 10, Excellent, (1000)
"Location"
The price is €153
includes taxes & fees
16 Mar - 17 Mar
Hampton Inn & Suites Gainesville-Downtown

Hyatt Place Gainesville Downtown

3.0 star property
9.2 out of 10, Wonderful, (795)
"The hotel location is so nice in down town, plenty of restaurants around. Staff were also so nice and helpful. The overall condition of the room was ok but restroom had some not nice smell, I would say not for not being clean but overall condition should be reconsidered. I didn’t like that there were not even a bottle of water as a welcome drink."
The price is €134
includes taxes & fees
23 Feb - 24 Feb
Hyatt Place Gainesville Downtown

Gainesville Lodge

2.0 star property
7.4 out of 10, Good, (491)
"Great service and clean rooms. Excellent value for this price point. I would definitely stay again "
The price is €80
includes taxes & fees
20 Feb - 21 Feb
Gainesville Lodge

Comfort Suites Gainesville near University

2.5 star property
9.2 out of 10, Wonderful, (995)
"Excellent friendly service from arrival to departure! "
The price is €105
includes taxes & fees
25 Feb - 26 Feb
Comfort Suites Gainesville near University

Quality Inn Gainesville near University

2.5 star property
7.0 out of 10, Good, (1004)
"Front desk was very helpful! We enjoyed walking over to the university! "
The price is €85
includes taxes & fees
4 Mar - 5 Mar
Quality Inn Gainesville near University

Regency Inn

2.5 star property
5.6 out of 10, (86)
"Newly renovated, staff and management were very nice"
The price is €77
includes taxes & fees
4 Mar - 5 Mar
Regency Inn

Home2 Suites by Hilton Gainesville Medical Center

3.0 star property
9.0 out of 10, Wonderful, (788)
"the room is clean and big"
The price is €127
includes taxes & fees
16 Mar - 17 Mar
Home2 Suites by Hilton Gainesville Medical Center

Value Lodge

2.0 star property
5.4 out of 10, (238)
"Nice rooms, great location, walkable to Florida campus, nice dining nearby, perfect for games with no need to drive. Really good and affordable option."
The price is €80
includes taxes & fees
20 Feb - 21 Feb
Value Lodge

Holiday Inn Gainesville - University Center by IHG

3.0 star property
7.6 out of 10, Good, (1000)
"Great catch for a quick trip; currently under renovations so no wifi during my stay but i didn’t need it. Staff is very attentive and accomodating to needs. My room was completely renovated and very comfortable and modern. Convenient parking on-site and within walking distance of the social scene in town. "
The price is €163
includes taxes & fees
16 Mar - 17 Mar
Holiday Inn Gainesville - University Center by IHG

Hotel Eleo at the University of Florida

3.0 star property
9.4 out of 10, Exceptional, (1193)
"I travel regularly in the USA and Internationally. I cannot think of another receptionist as engaging and polite as the one here. Who ever hired her should know that she is extraordinary. Everyone who meets her already knows. "
The price is €223
includes taxes & fees
2 Mar - 3 Mar
Hotel Eleo at the University of Florida

AC Hotel by Marriott Gainesville Downtown

2.5 star property
8.8 out of 10, Excellent, (396)
"Hells yea"
The price is €204
includes taxes & fees
13 Mar - 14 Mar
AC Hotel by Marriott Gainesville Downtown

Travelers Inn

2.0 star property
6.4 out of 10, (389)
"Great for the price. "
The price is €79
includes taxes & fees
24 Feb - 25 Feb
Travelers Inn

Hilton University of Florida Conference Center Gainesville

3.5 star property
8.4 out of 10, Very good, (1000)
"Staff were friendly and professional. Easy check in and put process. Rooms were spacious and clean. "
The price is €136
includes taxes & fees
2 Mar - 3 Mar
Hilton University of Florida Conference Center Gainesville

Fairfield Inn & Suites by Marriott Gainesville I-75

2.5 star property
9.6 out of 10, Exceptional, (1000)
"Great big room. Clean, easy to park. Close to all stores. Not far from university. Definitely will stay again. "
The price is €122
includes taxes & fees
16 Mar - 17 Mar
Fairfield Inn & Suites by Marriott Gainesville I-75

Aloft Gainesville University Area

3.0 star property
8.8 out of 10, Excellent, (1003)
"Nike at the desk as well as the bartender were both very helpful and polite. "
The price is €112
includes taxes & fees
23 Feb - 24 Feb
Aloft Gainesville University Area

Sleep Inn & Suites University/Shands

2.5 star property
8.4 out of 10, Very good, (1003)
"Very clean Convenient for doctor appointments at shands"
The price is €95
includes taxes & fees
2 Mar - 3 Mar
Sleep Inn & Suites University/Shands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santa Fe
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Santa Fe

Check out Alachua Sports Complex and O'Leno State Park—just a couple of the sights around Santa Fe.

Frequently asked questions

What's the best place for a stay in Santa Fe?

Located 18.6 mi (29.9 km) from the heart of Santa Fe, Country Inn & Suites by Radisson, Gainesville, FL is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Hyatt Place Gainesville Downtown and Best Western Gateway Grand. See all available top hotels, or vacation rentals in Santa Fe.

What are some of the best holiday rentals that Santa Fe has to offer?

Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️: This holiday home rental outside of Santa Fe is located on a river, and has a fireplace, a patio and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. Make the most of games in this rental home to help you unwind. See all vacation rentals in Santa Fe.

If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if cancelled before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.

What are some hotels with pools in Santa Fe?

Hom hotel + suites, Trademark Collection by Wyndham: Features free buffet breakfast, a pool and free self-parking. DoubleTree by Hilton Gainesville and Drury Inn & Suites Gainesville are two additional hotels that offer an on-site pool. View all hotels with pools in Santa Fe.

What is staying in Santa Fe like?

Travellers to Santa Fe will find plenty to explore and enjoy. There are 636 hotels and other accommodation options in the surrounding area. Find out more about Santa Fe.

What is there to see in Santa Fe?

Places to visit in the wider area include Alachua Sports Complex, O'Leno State Park and San Felasco Hammock Preserve State Park. You'll also find Devil's Milhopper Geological State Park and Gainesville Raceway in the area. Take a look at what more there is to see and do in Expedia's Santa Fe guide.

What's the weather like in Santa Fe?

The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 15°C. The rainiest months in Santa Fe are August, June, July and September, with each month seeing an average of 177 mm of rainfall.