Santa Lucia Holidays

Photo by William Keller

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Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most. Learn more about Santa Lucia
Temple of Apollo featuring a ruin and heritage elements

Ortigia

4 out of top 10 points of interest in this area

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Find hotels in Ortigia

Top hotels in Santa Lucia

Grande Albergo Alfeo

Grande Albergo Alfeo

4 out of 5
Via Nino Bixio 5 Syracuse SR
Fully refundableReserve now, pay when you stay
The price is €90 per night from 31 Mar to 1 Apr
€90
31 Mar - 1 Apr
includes taxes & fees
8.6/10 Excellent! (654 reviews)
Good front desk staff, welcoming breakfast staff, clean room and good area for walking to attractions.

Reviewed on 2 Dec 2025

Grande Albergo Alfeo
Caportigia Boutique Hotel

Caportigia Boutique Hotel

5 out of 5
Viale Montedoro 76 Syracuse SR
Fully refundableReserve now, pay when you stay
The price is €135 per night from 11 Mar to 12 Mar
€135
11 Mar - 12 Mar
includes taxes & fees
9.4/10 Exceptional! (267 reviews)
All staff were very polite and helpful. I liked they responded my questions quickly by messages. Good location to go to Ortigia, also to Neapolis. Room was spacious and very clean. We loved our stay, however we didn't feel luxurious as a five star hotel.

Reviewed on 26 Feb 2026

Caportigia Boutique Hotel
Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia

3 out of 5
Corso Umberto, 112 Syracuse SR
Get rates
Piccolo Hotel Casa Mia
See all 3,725 properties in Santa Lucia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Lucia holiday package cost?
Our Santa Lucia packages, which start from just , are the perfect way to save loads of cash. All you have to do is choose your preferred flights, hotels and rental cars to create your ideal escape.
How do I get a cheap travel package to Santa Lucia?
Combine your hotels and flights, throw in extras such as a rental car or activities, and save with a Santa Lucia holiday package. You won't just score big discounts on your escape — you'll have lots of choice at your fingertips too. When you book with Expedia, you can choose from more than 550 airlines and 1,000,000 hotels all over the world. Your affordable holiday begins right here, right now!
Where should I stay in Santa Lucia?
Take the hassle out of sightseeing by staying in a hotel right around the corner from Santa Lucia's iconic attractions. Cathedral of Syracuse and Temple of Apollo are two visitor favourites.
What are the top hotels in Santa Lucia?
If this will be your first time in Santa Lucia, book a room at Hotel Cavalieri or Paolanna Luxury Rooms. Both hotels offer friendly service and are popular options with many travellers.
How far in advance should I book my Santa Lucia holiday?
Smart travellers will likely want to reserve their seats early. You can normally compare international fares on Expedia up to 12 months before your flight. If you're purchasing tickets last minute, don't stress. Budget prices occasionally appear in the last weeks prior to departure.
What does an Expedia Santa Lucia travel package include?
Packages include hotels, flights and rental cars, but you can mix and match them to create your ideal Santa Lucia holiday. You can also add on some activities and experiences once you've made your booking. You're in charge! When you bundle your bookings with Expedia, you'll score discounts you won't find anywhere else.
What should I know before booking a Santa Lucia travel package?
You'll land impressive savings when you bundle your hotels, flights and rental cars into a package. Plus, booking everything in one place will make your trip planning easier. So why waste money or time? Whether you're putting together a ritzy romantic getaway or a budget family adventure, browse our package deals today.
Can I choose my airline with a Santa Lucia Expedia holiday package?
You can, and with more than 550 airlines to pick from globally, you have plenty of choice. Search the available options and find out which airline best fits your needs and budget.
If I'm not able to travel, can I cancel my Santa Lucia holiday package?
Yes, you can. We realise life doesn't always go to plan, so we're here to help if you have to make changes to your Santa Lucia holiday package. It may be possible to cancel or amend your itinerary at no cost if you've booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if your booking was made more than 24 hours ago. Visit our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.

Popular places to visit

Madonna delle Lacrime

You can study the exhibits at Madonna delle Lacrime, a museum with a story of its own, during your holiday in Syracuse. Wander the seaside in this culturally rich area.

Madonna delle Lacrime

Things to do

Siracusa: Ortygia Island Boat Tour with Grotto Visit

Siracusa: Ortygia Island Boat Tour with Grotto Visit

€25
per adult
Siracusa: Ortygia Island Boat Tour with Grotto Visit
Syracuse: Boat Tour of Ortigia Island and Sea Caves

Syracuse: Tour of Ortigia Island & Caves with Local Skipper

€25
per adult
100% of travellers recommend
Syracuse: Tour of Ortigia Island & Caves with Local Skipper
Syracuse: Cathedral entrance ticket with VR viewer experience

Syracuse: Cathedral entrance ticket with VR viewer experience

€8
per adult
Syracuse: Cathedral entrance ticket with VR viewer experience
See all activities in Syracuse
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.