Santo Spirito Holidays

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Price found within the past 48 hours. Click for updated prices.
Bernini Palace

Bernini Palace

5 out of 5
Duomo
per person
18 Apr - 21 Apr
found 1 hour ago
Return direct flight included
Dublin (DUB) to Florence (FLR)
9.6/10 Exceptional! (1,003 reviews)
Excellent hotel at the heart of Venice, with great staff and amenities.

Reviewed on 28 Jan 2025

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
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Duomo

5 out of top 10 points of interest in this area
4.5/5(418 area reviews)

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Via de' Calzaiuoli or Giotto's Campanile while you're exploring the neighbourhood.

Find hotels in Duomo

Top hotels in Santo Spirito

Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
The price is €109 per night from 16 Feb to 17 Feb
€109
includes taxes & fees
16 Feb - 17 Feb
9.2/10 Wonderful! (945 reviews)
"My mom and I loved our stay at the Palazzo Mannaioni in Florence. Roberto made us feel safe the minute we entered the Mannaioni and was very knowledgable of the area and accommodated anything we needed. The suites were in a great location, and the place was pristine."

Reviewed on 26 Jan 2025

Palazzo Mannaioni Suites
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
The price is €136 per night from 13 Feb to 14 Feb
€136
includes taxes & fees
13 Feb - 14 Feb
9.6/10 Exceptional! (467 reviews)
"Location is not great however excellent friendly staff. Parking is a bit of challenge as the entrance to the hotel is very narrow. Overall we enjoyed our stay."

Reviewed on 1 Feb 2025

Hotel Horto Convento
Hotel Calimala Florence
Hotel Calimala Florence
4 out of 5
Via Lamberti 5, Florence, FI
Fully refundableReserve now, pay when you stay
The price is €162 per night from 9 Feb to 10 Feb
€162
includes taxes & fees
9 Feb - 10 Feb
9.6/10 Exceptional! (644 reviews)
"The hotel is generally good but I was very bothered by the music and noise from a restaurant downstairs on the first night during my stay. I asked to change the room and the staff was helpful to arrange a quiet room for me on the next day. You may want to double check with the hotel on this point ..."

Reviewed on 7 Feb 2025

Hotel Calimala Florence
See all 9,321 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Spirito holiday package cost?
From just €998. Yes, you read that right. Our Santo Spirito packages are the best way to make your dollar go further. Bundle your favourite hotels, flights and rental car and explore this wonderful destination.
How do I get a cheap travel package to Santo Spirito?
If you love scoring a bargain, bundle your bookings into a Santo Spirito holiday package. Whether you need hotels, flights, activities or rental cars, you can book everything in one place. You’ll have endless choice at your fingertips as well. Expedia has more than 550 partner airlines and 1,000,000 hotels across the globe to choose from. Fly with who you want, stay in a place you like and save precious dollars — now that’s the ideal getaway!
What are the top hotels in Santo Spirito?
Reserve a room at Sweet Home Campuccio, 2 Double Bedrooms In San Frediano. It’s one of this area’s most sought-after hotels. Another well-known option in Santo Spirito is Residenza Oltrarno, An Elegant Apartment In The Historic Centre Of Florence.
How far in advance should I book my Santo Spirito holiday?
To score cheap prices, book as soon as you can. Airlines typically release tickets, along with some of the lowest fares, up to a year in advance. Hotels, activities and car rental should also be booked early to avoid disappointment. If you were hoping for a last-minute getaway in Santo Spirito, there are always lots of great deals on Expedia. Check them out now!
What does an Expedia Santo Spirito travel package include?
Rental cars, flights and hotels, or any combination of the three — it’s totally up to you. Whether you’re headed to Santo Spirito with the entire family or enjoying a solo break, there’s a bundle to match every budget and style. Once you’ve made your booking, why not add on a couple of tours as well?
What should I know before booking a Santo Spirito travel package?
Locking in all the parts of your trip together is one of the best ways to save. Combine car rentals, airfares and hotels into a neat little package. But you’re not restricted to hotels. Expedia features all sorts of properties, including holiday rentals like oceanfront condos and city residences. The list goes on!
Can I choose my airline with a Santo Spirito Expedia holiday package?
Yes — and it’s simple too. Expedia has access to more than 550 partner airlines all over the world. Our holiday packages give you the freedom to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Santo Spirito holiday package?
If your holiday plans in Santo Spirito have been upended, it’s a relief to know that it is possible to cancel your booking. If you made your booking within the last 24 hours, you may be eligible for a refund. If your booking is older than that, your airline, hotel or car rental company may charge a fee. For more details, check our Customer Service Portal.

Things to do

Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine

Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine

€29
per adult
88% of travellers recommend
Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine
Florence: Santa Monaca Church Italian Opera Concert Ticket

Florence: Santa Monaca Church Italian Opera Concert Ticket

€25
per adult
100% of travellers recommend
Florence: Santa Monaca Church Italian Opera Concert Ticket
Pastamania - Pasta making class

Pastamania - Florence Pasta Making Class

€49
per adult
100% of travellers recommend
Pastamania - Florence Pasta Making Class
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.