Photo by Cindy Keese

Holiday Rentals in Seneca

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Holiday Rentals in Seneca

Perfect Lake Hartwell Getaway - Gorgeous Lake Views!

10.0 out of 10, Exceptional, (80)
"We loved celebrating Christmas at this wonderful house. Three generations enjoyed the huge kitchen and multiple comfortable gathering spaces. Can’t wait to come back!"
Perfect Lake Hartwell Getaway - Gorgeous Lake Views!

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

9.2 out of 10, Wonderful, (74)
"Our stay was around when Helene Hurricane came through, Sept 27, 2024. The power was out so the cleaning person wasn't able to finish their task prior to our check in. However, there were clean linens and towels in the basement next to the washing machine. We also had trash bags, clean dishes and running water but no power. The cabin was nicely located in Seneca which wasn't far from the university. The cabin was also easy to find. "
Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Postcard Cabins Lake Hartwell

2.0 star property
10.0 out of 10, Exceptional, (2)
"Super cute, and comfy! A bit hard to drive up the hill with a car, but it was worth the quiet surroundings. Make sure to bring your own campfire stuff because they do charge extras. It has a full kitchen with plates and pans to cook if you want along with a mini fridge. "
The price is €71
includes taxes & fees
3 Mar - 4 Mar
Postcard Cabins Lake Hartwell

5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!

10.0 out of 10, Exceptional, (83)
"If you are looking for an awesome place to gather with family and/or friends, look no further. We gathered to celebrate our grand daughter’s graduation from Clemson. It was the perfect spot. A great space with lots to do and plenty of room to spread out. The younger adults played ping pong and darts. The kitchen is fully equipped with everything you could possibly need with a gorgeous table to enjoy meals together. The views are breath taking from the living area. I personally loved several...
The price is €1,536
includes taxes & fees
17 Feb - 18 Feb
5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!

Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!

9.8 out of 10, Exceptional, (42)
"Our son recently moved to Seneca. This was our first trip to visit him. This place was perfect for our family. There was an enough space to spread out and not be crowded. The dock and kayaks were enjoyed by our teen sons. The location was convenient and close to everything. We will definitely be staying here again. "
Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!

Spacious 8-bedroom house with WiFi and AC on peaceful Lake Keowee private cove.

9.6 out of 10, Exceptional, (5)
"Worked out good for our group "
Spacious 8-bedroom house with WiFi and AC on peaceful Lake Keowee private cove.

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

9.8 out of 10, Exceptional, (134)
"The property was clean, loaded with everything you need, and gave our large group room for privacy along with lots of time together around the beautiful dining table, the fire pit, and the pool table. Awesome stay and the host was wonderful to work with. Beautiful lake views as well!!"
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

Lakefront Cabin on Lake Keowee. Kayaks, paddle boards, modern & cozy!

10.0 out of 10, Exceptional, (3)
"Beautiful property and a Great Lake experience for young children. Homeowners were very responsive and helpful."
Lakefront Cabin on Lake Keowee. Kayaks, paddle boards, modern & cozy!

Keowee Splendor! Hot tub, dock, lake! 4br Retreat!

2.0 star property
The price is €584
includes taxes & fees
23 Feb - 24 Feb
Keowee Splendor! Hot tub, dock, lake! 4br Retreat!

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

10.0 out of 10, Exceptional, (217)
"Really appreciated the communication, cleanliness, and location. Great stay. "
😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.

9.8 out of 10, Exceptional, (342)
"Jim and Gail are super hospitable. We loved staying in the Lakehouse, and can’t wait for a chance to come back."
4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.

Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub

10.0 out of 10, Exceptional, (44)
"Everything was great! Plenty of space for large gatherings or for smaller groups, or even to get some quiet alone time. Lots of games and activities available. "
Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub

What a family lake house should be! Natural Beauty w/ space for each to enjoy!!!

9.0 out of 10, Wonderful, (29)
"Overall, I highly recommend this place for anyone looking to unwind and enjoy some beautiful scenery. The house was exactly as described in the listing, which made our stay even more enjoyable. Waking up to those stunning views of the lake every morning was such a treat—it really set the perfect tone for our days. Communication with the owner was a breeze. They were super responsive and made sure we had everything we needed. Plus, the check-in and check-out process was incredibly easy, which...
What a family lake house should be! Natural Beauty w/ space for each to enjoy!!!

Fall/Winter Specials! Big water views, private dock, pool table, 15 min Clemson!

10.0 out of 10, Exceptional, (38)
"Beautiful big house in a nice quiet neighborhood. A perfect spot for our family get together. There was lots of room for all to spread out. Has everything you need to cook and have fun. Pool table was a big hit for the week. Nice outdoor spaces to relax and enjoy the water/views. Owner was responsive when needed! We would definitely stay here again. "
Fall/Winter Specials! Big water views, private dock, pool table, 15 min Clemson!

Cozy Log Cabin near Clemson with Big Water Views

10.0 out of 10, Exceptional, (13)
"Great place to stay for a Clemson game weekend. Julie was very easy to communicate with and the house was perfect."
Cozy Log Cabin near Clemson with Big Water Views

Incredible 10 BR home with pool

9.0 out of 10, Wonderful, (2)
"House is virtually brand new. Well decorated. Spacious. Clean as a whistle. Heated pool/ hot tub. Billiards room. And a great property management company. "
Incredible 10 BR home with pool

The HART of Tiger Town! Lakefront home less than 4 miles to Clemson University

10.0 out of 10, Exceptional, (1)
"Thank you so much for letting us use your house. One of the guests who has ALS slipped out the shower and broke off the front corner of the lip to the toilet bowl. I have left money in the kitchen drawer to the right of the dishwasher to cover the expense"
The HART of Tiger Town! Lakefront home less than 4 miles to Clemson University

Pet-friendly Central Cottage: 2 Miles to Clemson!

3.0 star property
Pet-friendly Central Cottage: 2 Miles to Clemson!

Lake Keowee Resort Condo: Waterfront Balcony

10.0 out of 10, Exceptional, (61)
"The Tall Ship condo work out perfectly. We live in Keowee Key but our home is to small to accommodate both of our daughter and their families. The condo overlooking the lake, less then a mile from our house worked out great. Our agent was very accommodating allowing us to check in early to place a few Christmas decoration aroun before the family arrived."
Lake Keowee Resort Condo: Waterfront Balcony

Great weekend getaway just a mile from downtown!

10.0 out of 10, Exceptional, (8)
"The property is a great place to spend time with the family. Description is accurate. The host is very responsive and made our stay perfect. It is located close to almost everything. You can walk to the university within 15 minutes. Hiking trails are within a 10 minute drive."
Great weekend getaway just a mile from downtown!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other types of properties in Seneca you may be interested in

Lakeside Lodge Clemson

2.5 star property
9.0 out of 10, Wonderful, (789)
"We will be back"
The price is €128
includes taxes & fees
17 Feb - 18 Feb
Lakeside Lodge Clemson

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (577)
"Nice & efficient staff"
The price is €132
includes taxes & fees
9 Mar - 10 Mar
Hampton Inn & Suites Seneca-Clemson Area

Tru by Hilton Seneca Clemson

2.5 star property
9.2 out of 10, Wonderful, (672)
"2nd time staying here. Was just as wonderful as the my first stay. Staff was great!"
The price is €122
includes taxes & fees
23 Feb - 24 Feb
Tru by Hilton Seneca Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are there holiday rentals in Seneca?

Yes, there are holiday rentals close to the most popular sights in Seneca, or you can select a more secluded option if you're looking for a relaxing stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffee shops.

What are some of the best holiday rentals that Seneca has to offer?

5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!: This highly rated holiday home rental in Seneca is located on a lake, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 7 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. It offers a garden, a selection of games and 1 hot tub so that you can immerse yourself in your holiday. Another good choice for your trip to Seneca is Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!.

How many holiday rentals are there in Seneca?

Choose from 196 Expedia holiday rentals in Seneca for a memorable holiday.

What’s there to see and do in Seneca?

Cultural attractions include The Gauntlet and Oconee Community Theatre, whereas Keowee Reservoir and Lake Keowee are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Lake Hartwell are other places worth a visit.

What’s a holiday rental in Seneca like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Seneca. Holiday rentals offer extras such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about a sanitised environment, a holiday rental can offer a sense of seclusion away from public hotel lifts and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also get more space in a holiday rental than in a traditional hotel, which is another reason why a holiday rental is an attractive choice for family trips.