Houston Hotel Guide. Hotels in South Central Houston, Houston, United States of America
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Our top choices for South Central Houston hotels
8.0 out of 10, Very good, (36)
"Check in staff was friendly and room was clean."
Alfredo
The price is €85
includes taxes & fees
19 Dec - 20 Dec
8.4 out of 10, Very good, (1757)
"Loved the room, clean, friendly staff. Would reccomend :)"
Rolando
The price is €85
includes taxes & fees
25 Dec - 26 Dec
Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum DistrictSouth Central Houston
9.0 out of 10, Wonderful, (1000)
"Comfortable bed, very clean, very good food, quite, friendly stuff and hotel shuttle works easy."
Elena
The price is €162
includes taxes & fees
2 Jan - 3 Jan 2026
The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1013)
"Excellent breakfast and bar"
Misty
The price is €137
includes taxes & fees
19 Dec - 20 Dec
9.2 out of 10, Wonderful, (1000)
"Very clean room very polite staff"
David
The price is €163
includes taxes & fees
21 Dec - 22 Dec
DoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Houston Medical Center Hotel & SuitesSouth Central Houston
8.2 out of 10, Very good, (476)
"Solid hotel and amenities"
Kenneth
The price is €89
includes taxes & fees
15 Jan - 16 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in South Central Houston
Find the best South Central Houston areas for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston
Downtown Houston
Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Northside
While you're in Northside, take in top sights like The Heights Theater or Greenspoint Mall, and hop on the metro to see more of the city at Northline Transit Center/HCC Station or Melbourne/North Lindale Station.
Houston Heights
You'll enjoy the coffee shops and live music in Houston Heights. You might want to make time for a stop at The Heights Theater or Artcar Museum.
Top South Central Houston Hotel Reviews
The Westin Houston Medical Center/Museum District
10/10 Excellent
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- Aveva Stadium
- Daikin Park
- Discovery Green
- Eleanor Tinsley Park
- Gulfgate Shopping Center
- Visit Downtown Houston
- Visit Foster Place
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- Jesse H. Jones Hall
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