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21C Museum Hotel St Louis

4.5 star property
Luxury hotel with fitness centre and steam room

Choose dates to view prices

Photo gallery for 21C Museum Hotel St Louis

Exterior
Lobby
Indoor pool
Room, 1 King Bed, Corner
1 bedroom, in-room safe, desk, laptop workspace

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar
The current price is €158
includes taxes & fees
29 Jun - 30 Jun

Room options

Available filters for rooms
Showing 15 of 15 rooms

Loft, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Room (Bunk Bed)

Room (Bunk Bed)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • Sleeps 2
  • 1 Single Bunk Bed

Deluxe Room, Accessible (Accessible)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Double Room, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Shower/bath combination
Bathrobes
  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Luxury Double Room, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Shower/bath combination
Bathrobes
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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Exterior

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About the area

Map
1528 Locust street, St. Louis, MO, 63103

What's nearby

  • St. Louis Union Station - 6 min walk - 0.6 km
  • Enterprise Center - 6 min walk - 0.6 km
  • City Museum - 6 min walk - 0.6 km
  • Busch Stadium - 14 min walk - 1.2 km
  • Dome at America’s Center - 16 min walk - 1.3 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • Lambert-St. Louis International Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel near City Museum
A short walk from St. Louis Union Station and Enterprise Center, 21C Museum Hotel St Louis provides a coffee shop/cafe, dry cleaning/laundry services and a bar. Treat yourself to a massage or other spa services. In addition to a gym and a business centre, guests can connect to free in-room WiFi.
You'll also enjoy the following perks during your stay:
  • An indoor pool
  • Cooked-to-order breakfast (surcharge), valet parking (surcharge) and a lift
  • A billiards/pool table, a vending machine and smoke-free property
  • Luggage storage, ATM/banking services and meeting rooms
  • Guest reviews say great things the dining options, pool and helpful staff
Room features
All 104 rooms include comforts such as laptop-friendly workspaces and air conditioning, as well as perks such as free WiFi and desk chairs. Guest reviews highly rate the cleanliness rooms at the property.
More amenities include:
  • Free toiletries and hairdryers
  • Flat-screen TVs with premium channels
  • Wardrobes/cupboards, heating and daily housekeeping

Languages

English

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets are allowed for an extra charge of USD 100 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs only

Children and extra beds

Children are welcome
Rollaway/extra beds are not available.
Cots (infant beds) are not available

Payment types at the property

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

Does 21C Museum Hotel St Louis have a pool?

Yes, this property has an indoor pool.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of 19 Jun 2025, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on 29 Jun 2025 start from €153.90, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is 21C Museum Hotel St Louis pet-friendly?

Yes, dogs are allowed at this property. There's a fee of USD 100 per accommodation, per stay. Service animals are exempt from fees.

How much is parking at 21C Museum Hotel St Louis ?

Valet parking is available for USD 50 per day.

What time is check-in at 21C Museum Hotel St Louis ?

Check-in start time: 4:00 PM; check-in end time: 11:00 AM. Late check-in is available during limited hours.

What time is check-out at 21C Museum Hotel St Louis ?

Checkout is at 11:00 AM.

Where is 21C Museum Hotel St Louis located?

Located in Downtown West, this luxury hotel is within a 10-minute walk of Washington Avenue Historic District, Enterprise Center, and City Museum. St. Louis Union Station and America's Center Convention Complex are also within 15 minutes. 8th and Pine Station is 13 minutes by foot and St. Louis Gateway Station is 14 minutes.

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21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 858 out of 1189 reviews
Rating 8 - Good. 181 out of 1189 reviews
Rating 6 - Okay. 67 out of 1189 reviews
Rating 4 - Poor. 37 out of 1189 reviews
Rating 2 - Terrible. 46 out of 1189 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Korie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
very nice hotel felt worth the money
Stayed 1 night in Jun 2025

10/10 Excellent

Hasani

Liked: Cleanliness, amenities, property conditions & facilities
The pool and patio area was beautiful. Everything including the staff was 10/10.
Stayed 2 nights in Jun 2025

10/10 Excellent

Robert

Liked: Cleanliness, property conditions & facilities
Good hotel located within walking distance of the ballpark, arch, and numerous other parks.
Stayed 2 nights in May 2025

10/10 Excellent

Dominique

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and quiet and the rooms look just like the picture! Check in was fast.
Stayed 1 night in Jun 2025

10/10 Excellent

Jeffrey

Liked: Cleanliness, amenities, property conditions & facilities
The staff was amazing, room was awesome. Very close to the convention center
Stayed 5 nights in May 2025

10/10 Excellent

Kristie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great art all over and access to the galleries was a neat experience. Tim was clean and comfortable.
Stayed 1 night in Jun 2025

6/10 Okay

Jared

Liked: Cleanliness
The hotel was okay. But, the area around the hotel is not great. Also they don't have parking.
Stayed 3 nights in Jun 2025

10/10 Excellent

Cristina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely historic hotel. Amenities - pool and fitness center were excellent. Walkable to the City Museum. Would definitely stay here again.
Stayed 1 night in May 2025

10/10 Excellent

Jessica

Liked: Staff & service, amenities, property conditions & facilities
Great location, wonderful staff
Stayed 2 nights in Apr 2025

10/10 Excellent

Irena

Liked: Cleanliness, amenities, property conditions & facilities
Great
Stayed 1 night in Jun 2025

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I always love staying at this hotel! The decor is beautiful and the drinks and food are top notch!
Stayed 1 night in Apr 2025

10/10 Excellent

Ryan

Liked: Cleanliness, amenities, property conditions & facilities
This place has everything. Great food, great coffee, outstanding gym and pool area, and the rooms are top notch. Friendly and knowledgeable staff throughout. City Museum, Stadiums, and Arch all within walking distance. If you are staying in downtown St. Louis, I don't see another option.
Stayed 2 nights in May 2025

10/10 Excellent

Julian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Love the property! Staff and amenities were too tier! Only thing I would recommend is security on site to stop homeless from approaching guests.
Stayed 2 nights in Jun 2025

8/10 Good

Emma

Liked: Cleanliness, staff & service, property conditions & facilities
Great place in St. Louis.
Stayed 1 night in Apr 2025

10/10 Excellent

Jessica

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Spectacular interior! Good service. Would stay here again and highly recommend:)
Stayed 1 night in May 2025

10/10 Excellent

roland

Liked: Cleanliness, staff & service, property conditions & facilities
Very good
Stayed 1 night in Jun 2025

10/10 Excellent

Dallas

Liked: Cleanliness, amenities, property conditions & facilities
Had a great stay!
Stayed 1 night in Feb 2025

10/10 Excellent

Denise

Liked: Cleanliness, amenities, property conditions & facilities
The art in house was cool! I also liked the restaurant. My room was comfortable and quiet.
Stayed 1 night in May 2025

10/10 Excellent

Latisha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice and comfortable hotel.
Stayed 2 nights in Jan 2025

6/10 Okay

Jessica

Liked: Cleanliness, amenities
Disliked: Staff & service
Looks good and the toiletries brand is amazing
Stayed 1 night in Apr 2025

10/10 Excellent

Payton

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff were amazing. Highly recommend this hotel. This is the best hotel I’ve ever stayed at.
Stayed 1 night in Apr 2025

10/10 Excellent

Connor

Wonderful
Stayed 2 nights in May 2025

10/10 Excellent

David Michael

Liked: Cleanliness, amenities, property conditions & facilities
Great property
Stayed 4 nights in Apr 2025

2/10 Terrible

Ronald

Liked: Property conditions & facilities
Disliked: Cleanliness
We loved the hotel, it’s very beautiful. However our stay was terrible all around. We had an awful experience here and need help with our billing but the hotel staff is very unhelpful. Please help!!!!
Stayed 1 night in Jun 2025

10/10 Excellent

Samuel

Liked: Cleanliness, staff & service, property conditions & facilities
It’s easy to walk to most every venue I go to downtown. The hotel is amazingly beautiful.
Stayed 1 night in Apr 2025