
Uptown - Upper Duval Holidays
- Plan, book, travel with confidence
Better together
Save up to €185 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Where to stay in Uptown - Upper Duval
Find the best Uptown - Upper Duval areas and neighborhoods for the activities you enjoy most. Learn more about Uptown - Upper Duval

Old Town Key West
4 out of top 10 points of interest in this area
5/5(6 area reviews)
While visiting Old Town Key West, you might make a stop by sights like Duval Street and Saint Mary Star of the Sea.
Top hotels in Uptown - Upper Duval

Southernmost Beach Resort
1319 Duval Street, Key West, FL
Fully refundableReserve now, pay when you stay
The price is €324 per night from 3 Jun to 4 Jun
€324
includes taxes & fees
3 Jun - 4 Jun
8.6/10 Excellent! (2,452 reviews)
"Nice room with a great view. Convenient parking. Pool was nice but chairs were very close together. Phone did not work in our room, but no big deal. Maintenance request for phone and non-functional lamp was prompt, friendly and efficient. Overall great experience."
Reviewed on 5 May 2025

The Reach Key West, Curio Collection by Hilton
1435 Simonton Street, Key West, FL
Fully refundableReserve now, pay when you stay
The price is €338 per night from 26 May to 27 May
€338
includes taxes & fees
26 May - 27 May
8.2/10 Very Good! (945 reviews)
"This hotel is a little dated but that wasn’t an issue. It was clean but this"
Reviewed on 2 May 2025

The Southernmost Inn - Adults Only
525 United Street, Key West, FL
Fully refundableReserve now, pay when you stay
The price is €169 per night from 13 May to 14 May
€169
includes taxes & fees
13 May - 14 May
8/10 Very Good! (1,058 reviews)
"Great atmosphere"
Reviewed on 1 May 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit

Key West Butterfly and Nature Conservatory
4.5/5(10 reviews)
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Simonton Beach
Why not spend a care-free afternoon at Simonton Beach during your travels in Key West? While you're in the area, stroll along the seaside.
Things to do

Florida: Key West Overseas Highway App-Based Driving Audio Tour
€15
per traveller
76% of travellers recommend

Key West’s Old Town Treasures: A Self-Guided Audio Tour
€13
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.