Featured airlines
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 15% on select hotels after you book a flight*
- Newark to Panama City
- Miami to Panama City
- Milan to Panama City
- Amsterdam to Panama City
- Paris to Panama City
- Edinburgh to Panama City
- Sofia to Panama City
- Berlin to Panama City
- Dublin to Panama City
- Madrid to Panama City
- Vienna to Panama City
- Rome to Panama City
- San José to Panama City
- Austin to Panama City
Expedia's Latest Trends
Hotels
Mediterráneo Bay Hotel & ResortCasthotels Fuertesol BungalowsCourtyard Bedroom Ensuite, The Orchard, TerryglassBarceló Torre de Madrid3 Star Hotels in RavensdaleBarcelo Coconut Island PhuketThe First Collection at Jumeirah Village Circle, a Tribute Portfolio HotelThe Flying Pig Uptown HostelImperial HotelB&B KilmihilDolphin HouseApartments BallymacarbryHotels near Paris La Défense ArenaHotels in JonesboroughBest Western Hotel AstridB&B BoyleFamily Friendly Hotels in Southeast Ireland
Flights
Activities
*Available to Expedia members.