Cheap Flights from Minneapolis - St. Paul to San Diego

View €151 flight on Wed, 5 Nov 2025Opens in a new window

Popular airlines from Minneapolis to San Diego

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 15% on select hotels after you book a flight*
  • payments icon
    Earn twice
    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Minneapolis - St. Paul to San Diego (MSP-SAN)

Prices were available within the past 7 days and start at €151 for one-way flights and €173 for return, for the period specified. Prices and availability are subject to change. Additional terms apply.
Delta
Wed, 30 Jul - Wed, 6 Aug
MSP
Minneapolis
SAN
San Diego
€173
Return
Found 11 hours ago
Select Delta flight, departing Wed, 30 Jul from Minneapolis to San Diego, returning Wed, 6 Aug, priced at €173 Found 11 hours ago
American Airlines
Wed, 30 Jul - Wed, 6 Aug
MSP
Minneapolis
SAN
San Diego
€190
Return
Found 11 hours ago
Select American Airlines flight, departing Wed, 30 Jul from Minneapolis to San Diego, returning Wed, 6 Aug, priced at €190 Found 11 hours ago
Delta
Wed, 30 Jul - Wed, 6 Aug
MSP
Minneapolis
SAN
San Diego
€199
Return
Found 11 hours ago
Select Delta flight, departing Wed, 30 Jul from Minneapolis to San Diego, returning Wed, 6 Aug, priced at €199 Found 11 hours ago
American Airlines
Wed, 30 Jul - Wed, 6 Aug
MSP
Minneapolis
CLD
Carlsbad
€216
Return
Found 11 hours ago
Select American Airlines flight, departing Wed, 30 Jul from Minneapolis to Carlsbad, returning Wed, 6 Aug, priced at €216 Found 11 hours ago
American Airlines
Wed, 30 Jul - Wed, 6 Aug
MSP
Minneapolis
SAN
San Diego
€216
Return
Found 11 hours ago
Select American Airlines flight, departing Wed, 30 Jul from Minneapolis to San Diego, returning Wed, 6 Aug, priced at €216 Found 11 hours ago
United
Wed, 30 Jul - Wed, 6 Aug
MSP
Minneapolis
SAN
San Diego
€438
Return
Found 11 hours ago
Select United flight, departing Wed, 30 Jul from Minneapolis to San Diego, returning Wed, 6 Aug, priced at €438 Found 11 hours ago
*Available to Expedia members.