Featured airlines
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 15% on select hotels after you book a flight*
- Newark to Panama City
- Raleigh to Panama City
- Boston to Panama City
- Amsterdam to Panama City
- Paris to Panama City
- Bucharest to Panama City
- Sofia to Panama City
- Dublin to Panama City
- Budapest to Panama City
- Madrid to Panama City
- Lima to Panama City
- Cartagena to Panama City
- London to Panama City
- Bogotá to Panama City
Expedia's Latest Trends
Hotels
Hotels in Saint-Jean-Pied-de-PortLuxury Studio Flat just off Exmouth MarketGrand Hotel Villa SerbelloniHyatt Herald Square New YorkHotels in The LibertiesLong Quay HouseHotels with Pool in StillorganMaison des AmbassadeursBBIreland Hotels in Carrick-on-SuirHistoric Hotels in BallybunionHotels in OranmoreCanifor HotelB&B GlasgowApartments BurnfootVan der Valk Amsterdam AmstelGrand Hyatt Barcelona
Holiday Rentals
*Available to Expedia members.