Featured airlines
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 15% on select hotels after you book a flight*
- Brussels to Panama City
- Amsterdam to Panama City
- Florianópolis to Panama City
- Sofia to Panama City
- Edinburgh to Panama City
- Warsaw to Panama City
- Guadalajara to Panama City
- Curitiba to Panama City
- Dublin to Panama City
- Budapest to Panama City
- Madrid to Panama City
- Nashville to Panama City
- Cartagena to Panama City
- Lisbon District to Panama City
- Venice to Panama City
- Quito to Panama City
- San Francisco to Panama City
Expedia's Latest Trends
Hotels
tent Lloret de MarHotels in Mount MellerayB&B InnishannonHoliday Inn Glasgow City Centre Theatreland by IHGHotels in Kos TownAthina Luxury SuitesResorts FuerteventuraVillas JoinalHard Rock Hotel MaldivesB&B EnniskerryHotels with Spa in WestportHodson Bay HotelImmaculate 5-bed House in Glin, LimerickHotels near St. Lukes General HospitalFamily Friendly Hotels in MaltaGalley Bay Resort & SpaCiutat de Barcelona
Flights
Packages
General
*Available to Expedia members.