Featured airlines

- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 15% on select hotels after you book a flight*
Cheap flights from Des Moines to Florence (DSM-FLR)
Prices were available within the past 7 days and start at €506 for one-way flights and €806 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, 22 Mar - Wed, 2 Apr
DSM
Des Moines
FLR
Florence
€806 Return, found 1 day ago
€806
Return
found 1 day ago

Sat, 22 Mar - Wed, 2 Apr
DSM
Des Moines
FLR
Florence
€812 Return, found 1 day ago
€812
Return
found 1 day ago

Sat, 22 Mar - Wed, 2 Apr
DSM
Des Moines
FLR
Florence
€830 Return, found 1 day ago
€830
Return
found 1 day ago

Sat, 22 Mar - Wed, 2 Apr
DSM
Des Moines
FLR
Florence
€854 Return, found 1 day ago
€854
Return
found 1 day ago

Sat, 22 Mar - Wed, 2 Apr
DSM
Des Moines
FLR
Florence
€856 Return, found 1 day ago
€856
Return
found 1 day ago

Sat, 22 Mar - Wed, 2 Apr
DSM
Des Moines
FLR
Florence
€858 Return, found 1 day ago
€858
Return
found 1 day ago

Sat, 22 Mar - Wed, 2 Apr
DSM
Des Moines
FLR
Florence
€858 Return, found 1 day ago
€858
Return
found 1 day ago

Sat, 22 Mar - Wed, 2 Apr
DSM
Des Moines
FLR
Florence
€918 Return, found 1 day ago
€918
Return
found 1 day ago

Sat, 22 Mar - Wed, 2 Apr
DSM
Des Moines
FLR
Florence
€943 Return, found 1 day ago
€943
Return
found 1 day ago

Sat, 22 Mar - Wed, 2 Apr
DSM
Des Moines
FLR
Florence
€943 Return, found 1 day ago
€943
Return
found 1 day ago
Origin airport | Des Moines Intl. |
Destination airport | Peretola |
Return price | €805 |
Distance | 7882 km |
Perfect flights from Des Moines to Florence
Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Des Moines to Florence. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
Picture yourself strolling through the streets of , surrounded by breathtaking architecture and absorbing the vibrant atmosphere of this captivating city. Indulge in the mouth-watering local specialties, from tantalizing street food to exquisite fine dining. With Expedia, you can experience all of this and more, without sacrificing your budget.
Our flexible Des Moines Intl. to Peretola ticket options cater to your travel preferences, with incredible one-way fares from €506 and roundtrip prices from €806. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at Peretola and explore and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your to travel arrangements today and embark on the journey of a lifetime in Florence.
- Trending Routes
- Trending Flights
- Top Flights Destinations
- More Airlines
- Cheap Flights from Other Airports
- Expedia's Latest Trends
Top Routes from Des Moines
Top Routes to Florence
- Riga to Florence (RIX - FLR)
- Zagreb to Florence (ZAG - FLR)
- London to Florence (LCY - FLR)
- Prague to Florence (PRG - FLR)
- Belgrade to Florence (BEG - FLR)
- Cork to Florence (ORK - FLR)
- Bucharest to Florence (OTP - FLR)
- Sofia to Florence (SOF - FLR)
- Tirana to Florence (TIA - FLR)
- Dublin to Florence (DUB - FLR)
- Shannon to Florence (SNN - FLR)
- Vienna to Florence (VIE - FLR)
Top Routes to Florence
Top Flight Destinations
- Flights to Rome
- Flights to Milan
- Flights to Florence
- Flights to Venice
- Flights to Naples
- Flights to Sorrento
- Flights to Positano
- Flights to Bologna
- Flights to Palermo
- Flights to Taormina
- Flights to Amalfi
- Flights to Verona
- Flights to Turin
- Flights to Bari
- Flights to Catania
- Flights to Matera
- Flights to Olbia
- Flights to Pisa
- Flights to Bellagio
- Flights to Genoa
Expedia's Latest Trends
Hotels
Flights
Flights from Cork (ORK) to Pisa (PSA)Flights from Dublin (DUB) to Pisa (PSA)Flights from London (LHR) to Venice (VCE)Flights from Shannon (SNN) to Venice (VCE)Flights from Dublin (DUB) to Sommacampagna (VRN)Flights from Dublin (DUB) to Venice (VCE)Flights from Shannon (SNN) to Pisa (PSA)Flights from Dublin (DUB) to Bolzano (BZO)Flights from Dublin (DUB) to Lamezia Terme (SUF)Flights from Venice (VCE) to Rome (FCO)Flights from Pisa (PSA) to Dublin (DUB)Flights from Belfast (BHD) to Pisa (PSA)Flights from Cork (ORK) to Venice (VCE)Flights from Dublin (DUB) to Florence (FLR)Flights from Crumlin (BFS) to Venice (VCE)Flights from Reggio Calabria (REG) to Dublin (DUB)Flights from ROM-All Airports to RIO-All AirportsFlights from Belfast (BHD) to Bologna (BLQ)Flights from Bologna (BLQ) to Dublin (DUB)Flights from RIO-All Airports to ROM-All AirportsFlights from Pontecagnano Faiano (QSR) to Dublin (DUB)Flights to PragueFlights from Dublin (DUB) to Bologna (BLQ)Flights from Venice (VCE) to Cork (ORK)
*Available to Expedia members.