
Popular airlines from Chicago O'Hare Intl. Airport (ORD) to Columbia, MO (COU-Columbia Regional)
- Aer Lingus
Aer Lingus
- Lufthansa
Lufthansa
- British Airways
British Airways
- Turkish Airlines
Turkish Airlines
- American Airlines
American Airlines
- Air Serbia
Air Serbia
- Swiss International Air Lines
Swiss International Air Lines
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Cheap flights from Chicago to Columbia (ORD-COU)
Prices were available within the past 7 days and start at for one-way flights and €241 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, 21 May - Thu, 5 Jun
ORD
Chicago
COU
Columbia
€241 Return, found 6 days ago
€241
Return
found 6 days ago

Wed, 21 May - Thu, 5 Jun
ORD
Chicago
COU
Columbia
€249 Return, found 6 days ago
€249
Return
found 6 days ago

Wed, 21 May - Fri, 6 Jun
ORD
Chicago
COU
Columbia
€258 Return, found 6 days ago
€258
Return
found 6 days ago

Wed, 21 May - Thu, 5 Jun
ORD
Chicago
COU
Columbia
€302 Return, found 6 days ago
€302
Return
found 6 days ago

Wed, 21 May - Fri, 6 Jun
ORD
Chicago
COU
Columbia
€310 Return, found 6 days ago
€310
Return
found 6 days ago

Wed, 21 May - Thu, 5 Jun
ORD
Chicago
COU
Columbia
€343 Return, found 6 days ago
€343
Return
found 6 days ago

Wed, 21 May - Thu, 5 Jun
ORD
Chicago
COU
Columbia
€351 Return, found 6 days ago
€351
Return
found 6 days ago

Wed, 21 May - Thu, 5 Jun
ORD
Chicago
COU
Columbia
€360 Return, found 6 days ago
€360
Return
found 6 days ago

Wed, 21 May - Fri, 6 Jun
ORD
Chicago
COU
Columbia
€374 Return, found 6 days ago
€374
Return
found 6 days ago

Wed, 21 May - Fri, 6 Jun
ORD
Chicago
COU
Columbia
€383 Return, found 6 days ago
€383
Return
found 6 days ago

Wed, 21 May - Thu, 5 Jun
ORD
Chicago
COU
Columbia
€403 Return, found 6 days ago
€403
Return
found 6 days ago

Wed, 21 May - Thu, 5 Jun
ORD
Chicago
COU
Columbia
€412 Return, found 6 days ago
€412
Return
found 6 days ago

Wed, 21 May - Fri, 6 Jun
ORD
Chicago
COU
Columbia
€434 Return, found 6 days ago
€434
Return
found 6 days ago

Wed, 21 May - Thu, 5 Jun
ORD
Chicago
COU
Columbia
€478 Return, found 6 days ago
€478
Return
found 6 days ago

Wed, 21 May - Fri, 6 Jun
ORD
Chicago
COU
Columbia
€494 Return, found 6 days ago
€494
Return
found 6 days ago

Wed, 21 May - Fri, 6 Jun
ORD
Chicago
COU
Columbia
€503 Return, found 6 days ago
€503
Return
found 6 days ago

Wed, 21 May - Thu, 5 Jun
ORD
Chicago
COU
Columbia
€527 Return, found 6 days ago
€527
Return
found 6 days ago

Wed, 21 May - Thu, 5 Jun
ORD
Chicago
COU
Columbia
€535 Return, found 6 days ago
€535
Return
found 6 days ago

Wed, 21 May - Fri, 6 Jun
ORD
Chicago
COU
Columbia
€555 Return, found 6 days ago
€555
Return
found 6 days ago

Wed, 21 May - Fri, 6 Jun
ORD
Chicago
COU
Columbia
€583 Return, found 6 days ago
€583
Return
found 6 days ago
Frequently asked questions
Travel information
Travel information
Origin airport | O'Hare Intl. |
Destination airport | Columbia Regional |
Return price | €240 |
Distance | 503 km |
Book with confidence
Book with confidence
Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Chicago to Columbia. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
Picture yourself strolling through the streets of , surrounded by breathtaking architecture and absorbing the vibrant atmosphere of this captivating city. Indulge in the mouth-watering local specialties, from tantalizing street food to exquisite fine dining. With Expedia, you can experience all of this and more, without sacrificing your budget.
Our flexible O'Hare Intl. to Columbia Regional ticket options cater to your travel preferences, with incredible one-way fares and roundtrip prices from €241. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at Columbia Regional and explore and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your to travel arrangements today and embark on the journey of a lifetime in Columbia.
Explore a world of travel with Expedia
Explore a world of travel with Expedia
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Expedia's Latest Trends
Flights
Flights from New York (JFK) to Chicago (ORD)Flights from Chicago (ORD) to Shannon (SNN)Flights from Boston (BOS) to Chicago (ORD)Flights from Chicago (ORD) to Orlando (MCO)Flights from Shannon (SNN) to Chicago (ORD)Flights from Chicago (ORD) to Los Angeles (LAX)Flights from Chicago (ORD) to San Diego (SAN)Flights from Dublin (DUB) to Chicago (ORD)Flights from Chicago (ORD) to Dallas (DFW)Flights from Naples (NAP) to Chicago (ORD)Flights from London (LHR) to Chicago (ORD)Flights from Chicago (ORD) to Las Vegas (LAS)Flights from Chicago (ORD) to Dublin (DUB)Flights from Chicago (ORD) to St. Louis (STL)Flights from Philadelphia (PHL) to Chicago (ORD)Flights from Chicago (ORD) to Boston (BOS)Flights from Chicago (ORD) to Minneapolis - St. Paul (MSP)Flights from Los Angeles (LAX) to Chicago (ORD)Flights from Chicago (ORD) to Miami (MIA)Flights from Orlando (MCO) to Chicago (ORD)Flights from Chicago (ORD) to Nashville (BNA)Flights from Chicago (ORD) to Seattle (SEA)Flights from Cork (ORK) to Chicago (ORD)Flights from Vancouver (YVR) to Chicago (ORD)Flights from Chicago (ORD) to Indianapolis (IND)Flights from New York (LGA) to Chicago (ORD)Flights from Chicago (ORD) to New York (LGA)Flights from Toronto (YYZ) to Chicago (ORD)Flights from Chicago (ORD) to Detroit (DTW)Flights from Chicago (ORD) to San Francisco (SFO)
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