Photo by Amber Palmer

Jacksonville Hotel Guide - Mayo Clinic Florida hotels in Jacksonville, United States of America.

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
16 Jul - 17 Jul
Tomorrow
17 Jul - 18 Jul
This weekend
18 Jul - 20 Jul
Next weekend
25 Jul - 27 Jul

Filter by

Guest rating
Guest rating
Property class

Top Trending Hotels Near Mayo Clinic Florida

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Reception

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
9.4 out of 10, Exceptional, (406)
"The place was clean and staff was wonderful. Will be staying again!"
The price is €158
includes taxes & fees
9 Aug - 10 Aug
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
TownePlace Suites by Marriott Jacksonville East
Terrace/patio

TownePlace Suites by Marriott Jacksonville East

3.0 star property
9.2 out of 10, Wonderful, (475)
"Close to 95, clean, friendly , lots of parking and close to beach. "
The price is €118
includes taxes & fees
27 Jul - 28 Jul
TownePlace Suites by Marriott Jacksonville East
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Terrace/patio

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 star property
9.0 out of 10, Wonderful, (1000)
"I loved our stay"
The price is €115
includes taxes & fees
27 Jul - 28 Jul
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Terrace/patio

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3.0 star property
8.4 out of 10, Very good, (725)
"Close to mayo"
The price is €157
includes taxes & fees
26 Jul - 27 Jul
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Lobby sitting area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 star property
8.4 out of 10, Very good, (1006)
"Staff was great and the hotel had been totally refurbished. "
The price is €112
includes taxes & fees
18 Jul - 19 Jul
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Element Jacksonville Beach
Lobby

Element Jacksonville Beach

3.0 star property
9.6 out of 10, Exceptional, (484)
"It was a clean hotel with fairly comfortable beds. "
The price is €132
includes taxes & fees
10 Aug - 11 Aug
Element Jacksonville Beach
Holiday Inn Express Jacksonville Beach by IHG
Free daily buffet breakfast

Holiday Inn Express Jacksonville Beach by IHG

2.5 star property
9.2 out of 10, Wonderful, (1000)
"Clean convenient and close to dining "
The price is €109
includes taxes & fees
20 Jul - 21 Jul
Holiday Inn Express Jacksonville Beach by IHG
Salt Air Inn & Suites
BBQ/picnic Area

Salt Air Inn & Suites

2.5 star property
9.8 out of 10, Exceptional, (343)
"Great place to stay"
The price is €155
includes taxes & fees
17 Jul - 18 Jul
Salt Air Inn & Suites
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Exterior

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

2.5 star property
8.8 out of 10, Excellent, (1018)
"Very nice hotel and great staff"
The price is €123
includes taxes & fees
3 Aug - 4 Aug
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Four Points by Sheraton Jacksonville Beachfront
Exterior

Four Points by Sheraton Jacksonville Beachfront

3.0 star property
9.2 out of 10, Wonderful, (1005)
"Very nice for a quick get away"
The price is €182
includes taxes & fees
10 Aug - 11 Aug
Four Points by Sheraton Jacksonville Beachfront
Ponte Vedra Inn & Club
Reception

Ponte Vedra Inn & Club

5.0 star property
9.4 out of 10, Exceptional, (802)
"We enjoyed our stay Friendly Professional Staff "
The price is €454
includes taxes & fees
1 Aug - 2 Aug
Ponte Vedra Inn & Club
Margaritaville Jacksonville Beach
On the beach, white sand, surfing, kayaking

Margaritaville Jacksonville Beach

2.5 star property
9.0 out of 10, Wonderful, (3002)
"We loved staying here! The room was very comfortable and the beach walk area was awesome."
Margaritaville Jacksonville Beach
The Lodge and Club at Ponte Vedra Beach
Beach/ocean view

The Lodge and Club at Ponte Vedra Beach

5.0 star property
9.4 out of 10, Exceptional, (670)
"Loved our stay, my sixth at this property. JR the waiter at breakfast at the Inn, was delightful!Cant wait to come back!"
The price is €543
includes taxes & fees
30 Jul - 31 Jul
The Lodge and Club at Ponte Vedra Beach
Hampton Inn Jacksonville Beach/Oceanfront
2 outdoor pools, pool umbrellas, pool loungers

Hampton Inn Jacksonville Beach/Oceanfront

3.0 star property
9.2 out of 10, Wonderful, (2319)
"Great hotel for the price and ocean view room."
The price is €178
includes taxes & fees
10 Aug - 11 Aug
Hampton Inn Jacksonville Beach/Oceanfront
Best Western Oceanfront
On the beach

Best Western Oceanfront

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Enjoyed our stay. Great location. "
The price is €129
includes taxes & fees
10 Aug - 11 Aug
Best Western Oceanfront
The Hotel Palms
Standard Room, 2 Queen Beds, Non Smoking

The Hotel Palms

3.5 star property
9.6 out of 10, Exceptional, (287)
"Easy comfy convenient. "
The price is €184
includes taxes & fees
3 Aug - 4 Aug
The Hotel Palms
Springhill Suites By Marriott Jacksonville Beach Oceanfront
On the beach, windsurfing

Springhill Suites By Marriott Jacksonville Beach Oceanfront

4.0 star property
9.0 out of 10, Wonderful, (526)
"It was nice, very clean and the staff was great"
The price is €162
includes taxes & fees
3 Aug - 4 Aug
Springhill Suites By Marriott Jacksonville Beach Oceanfront
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Exterior

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

2.5 star property
9.4 out of 10, Exceptional, (1013)
"Clean hotel, would stay here again"
The price is €109
includes taxes & fees
10 Aug - 11 Aug
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
AC Hotel Jacksonville St Johns Town Center
Lounge

AC Hotel Jacksonville St Johns Town Center

2.5 star property
9.4 out of 10, Exceptional, (119)
"Great place to stay, easy in/out, nice facilities and plenty to do in the area. "
The price is €175
includes taxes & fees
17 Jul - 18 Jul
AC Hotel Jacksonville St Johns Town Center
TownePlace Suites by Marriott® Jacksonville Mayport
Front of property – evening/night

TownePlace Suites by Marriott® Jacksonville Mayport

3.0 star property
10.0 out of 10, Exceptional, (7)
"Great looking property with friendly staff. Conveniently located near Naval Station Mayport. Also close enough to get to Jacksonville Beach with a short drive. "
The price is €115
includes taxes & fees
24 Jul - 25 Jul
TownePlace Suites by Marriott® Jacksonville Mayport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 35 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Another good choice is Residence Inn By Marriott Jacksonville - Mayo Clinic Area, located just 0.7 mi (1.1 km) away.

How many hotels are there near Mayo Clinic Florida?

Expedia has 35 hotels and other accommodation options within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Wilson Center For the Arts and Players by the Sea. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Gonzales Park. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.