Osprey Hotel Guide - Hotels with Spa in Osprey, Florida

March 2025

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Top Osprey Hotels with Spa

Casey Key Resorts - Mainland

3.0 star property
8.6 out of 10, Excellent, (1046)
"Pool area was great. "
The price is €240
includes taxes & fees
12 Mar - 13 Mar
Casey Key Resorts - Mainland

The Shoreland Hideaway 4BR & 2BA jacuzzi, minutes from Siesta Key

9.0 out of 10, Wonderful, (12)
"This is an older property so the rooms are spacious. The house suited our needs. Everything is on one level. Great for our toddler and our grandmother with her walker. The small pool was fun for our little guy and we really appreciated the net barrier to dissuade him from jumping in the pool at other times. We had some minor issues and the management company was very responsive even though it was Christmas. The house was super clean, the kitchen was set up for basic meals for a large group....
The Shoreland Hideaway 4BR & 2BA jacuzzi, minutes from Siesta Key

Pool, Hot tub, Close to Beaches, Shopping, More!

9.8 out of 10, Exceptional, (21)
"What a wonderful place to relax! Will definitely recommend to family and friends and even come back to stay!"
Pool, Hot tub, Close to Beaches, Shopping, More!

Newly Remodeled Villa in Osprey

9.8 out of 10, Exceptional, (28)
"All was exceptional."
Newly Remodeled Villa in Osprey

Family Guesthouse with Pool Views minutes from Nokomis Beach

8.0 out of 10, Very good, (3)
"Excellent property overall!!!! Host was very responsive and answered any questions very quickly. The space is clean and fresh!!! Very comfortable and great quality. Would definitely stay again! Thanks!!!"
Family Guesthouse with Pool Views minutes from Nokomis Beach

3 Bedroom Penthouse with Stunning Sunset Views of Blackburn Bay!

9.6 out of 10, Exceptional, (9)
"My sister and I planned a mini-vacay with our two daughters and had an amazing time! The condo is beautiful, just like the pics! I wasn’t sure of what to expect but we were all very happy. Thanks for a great stay"
3 Bedroom Penthouse with Stunning Sunset Views of Blackburn Bay!

Bright & Comfortable Florida Cottage, Within 15 Min to Siesta and Nokomis Beach

10.0 out of 10, Exceptional, (1)
"Thx - great cottage."
Bright & Comfortable Florida Cottage, Within 15 Min to Siesta and Nokomis Beach

Private guest house with king bed & loft. Deck with hot tub and putting green

10.0 out of 10, Exceptional, (1)
"Everything was just as described. Parking was easy. The king size bed was very comfortable. I loved the fun faucet in the bathroom. The kitchen is pretty darn high end. They really didn't seem to skimp on anything. We pretty much spent all of our time at the house in the hot tub. The neighborhood is delightful. We could've walked to the restaurants we visited, which were also great. A very easy drive to Venice beach where we found our intended shark teeth. We were talking about coming back and...
Private guest house with king bed & loft. Deck with hot tub and putting green

Paradise with a pool, pier and private beach area

9.0 out of 10, Wonderful, (18)
"The location of this house is spectacular! Beautiful view of the Intercostal ! I was so excited to share this house with friends and family. There were several things that were not what I would have expected to encounter in a home of this stature. There were at least 3 chairs and a sofa that were badly soiled. Drawers in the kitchen were dirty with someone else’s crumbs. I have a dog and I know how important it is to pick up after her but upon my arrival, I was checking things out and noticed...
Paradise with a pool, pier and private beach area

A Tropical 2 Bedroom/2 Bath House w/ Pool and Dock

10.0 out of 10, Exceptional, (5)
"Great place to stay!!! Clean and comfortable quiet neighborhood everything was great!!!!"
A Tropical 2 Bedroom/2 Bath House w/ Pool and Dock
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to holiday at a spa hotel in Osprey?
Treat yourself to some time in a luxurious spa hotel and you won’t regret it. Travellers like the beaches and top-notch bars in Osprey so get ready for a day of fun. Enjoy the shops and many popular restaurants during your holiday. Spa hotels are the perfect way to break out of your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Osprey?
Casey Key Resorts - Mainland is a top spa hotel featuring a pool, a bar and a restaurant.
How many spa hotels will I find in Osprey?
Among Expedia’s 34 accommodation options in Osprey, there are 2 spa hotels.
What's there to see and do in Osprey?
Experience Osprey and visit Turtle Beach, Nokomis Beach and Oscar Scherer State Park. If you have some spare time during your trip, you might want to check out Jim Neville Marine Preserve and Nancy’s Consignments.
What is a Osprey spa hotel?
Spa hotels in Osprey provide lodging and have a full on-site spa which offers services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.