Medical Center District

San Antonio

Photo by Linda Cronan

Popular places to visit

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
2.5 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is €97 per night from 9 Apr to 10 Apr
€97
includes taxes & fees
9 Apr - 10 Apr
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,367 reviews)
"The room was nice and cold which is very hard to find in other hotels"

Reviewed on 30 Mar 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center
3.5 out of 5
3233 NW Loop 410, San Antonio, TX
The price is €108 per night from 20 Apr to 21 Apr
€108
includes taxes & fees
20 Apr - 21 Apr
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free area shuttle, and room service. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,004 reviews)
"I would stay here again! It was a nice hotel and right off the hwy way. Less than 20 mins from seaworld"

Reviewed on 27 Mar 2025

San Antonio Marriott Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
3 out of 5
9806 Interstate Hwy 10 W, San Antonio, TX
The price is €109 per night from 9 Apr to 10 Apr
€109
includes taxes & fees
9 Apr - 10 Apr
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,207 reviews)
"Loved the breakfasts and happy hour. Great accommodations. Will definitely recommend to friends"

Reviewed on 30 Mar 2025

Drury Inn & Suites San Antonio Northwest Medical Center
Riverwalk Plaza
Riverwalk Plaza
4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
Fully refundable
The price is €122 per night from 15 Apr to 16 Apr
€122
includes taxes & fees
15 Apr - 16 Apr
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the ...
8/10 Very Good! (4,973 reviews)
"Conveniently located"

Reviewed on 30 Mar 2025

Riverwalk Plaza
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
3 out of 5
303 Blum Street, San Antonio, TX
The price is €106 per night from 8 Apr to 9 Apr
€106
includes taxes & fees
8 Apr - 9 Apr
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.6/10 Good! (3,517 reviews)
"We enjoyed our stay at the La Quinta Inn. Staff was very pleasant (especially those in breakfast area), always busy and helpful."

Reviewed on 30 Mar 2025

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Drury Plaza Hotel San Antonio Riverwalk
Drury Plaza Hotel San Antonio Riverwalk
3 out of 5
105 S Saint Marys Street, San Antonio, TX
The price is €131 per night from 9 Apr to 10 Apr
€131
includes taxes & fees
9 Apr - 10 Apr
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (3,262 reviews)
"The staff couldn't have been better. Everyone was friendly and helpful! Our room was clean and neat. The pool and exercise room are clean with good equipment."

Reviewed on 31 Mar 2025

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Los Angeles Heights

While Northwest Los Angeles Heights may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like San Antonio Zoo and Aquarium and San Antonio River.

Northwest Los Angeles Heights
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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Dub Farris Athletic Complex are top sights worth seeing.

Northwest Side
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or San Antonio River while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

While visiting Tobin Hill, you might make a stop by sights like San Antonio River and Pearl District.

Tobin Hill
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Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.

Uptown

Medical Center District

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