Photo by Linda Cronan

San Antonio Hotel Guide. Hotels in Medical Center District, San Antonio, United States of America

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Tonight
23 Jun - 24 Jun
Tomorrow
24 Jun - 25 Jun
This weekend
27 Jun - 29 Jun
Next weekend
4 Jul - 6 Jul

Filter by

Guest rating
Guest rating
Property class

Top Trending Hotels Near Medical Center District, San Antonio

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Lobby

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 star property
9.0 out of 10, Wonderful, (889)
"We enjoy staying at this Fairfield because it is very close to the medical center"
The price is €93
includes taxes & fees
6 Jul - 7 Jul
Fairfield Inn & Suites by Marriott San Antonio Medical Center
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Front of property

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3.0 star property
8.6 out of 10, Excellent, (2645)
"Good stay, great customer service, and great location "
The price is €89
includes taxes & fees
25 Jun - 26 Jun
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Park Inn by Radisson
Reception

Park Inn by Radisson

2.0 star property
7.2 out of 10, Good, (1002)
"Was perfect "
The price is €68
includes taxes & fees
6 Jul - 7 Jul
Park Inn by Radisson
SpringHill Suites by Marriott San Antonio Medical Center/NW
Premium bedding, pillow-top beds, in-room safe, desk

SpringHill Suites by Marriott San Antonio Medical Center/NW

3.0 star property
8.8 out of 10, Excellent, (1002)
"Very clean and accomodating."
The price is €112
includes taxes & fees
24 Jun - 25 Jun
SpringHill Suites by Marriott San Antonio Medical Center/NW
Drury Inn & Suites San Antonio Northwest Medical Center
Lobby

Drury Inn & Suites San Antonio Northwest Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1252)
"Nice stay overall"
The price is €103
includes taxes & fees
29 Jun - 30 Jun
Drury Inn & Suites San Antonio Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio
Lobby

Courtyard by Marriott Medical Center San Antonio

3.0 star property
8.6 out of 10, Excellent, (1003)
"Friendly helpful staff, quiet area, lots of dining options, easy parking "
The price is €95
includes taxes & fees
6 Jul - 7 Jul
Courtyard by Marriott Medical Center San Antonio
San Antonio Marriott Northwest Medical Center
Cocktail bar

San Antonio Marriott Northwest Medical Center

3.5 star property
8.4 out of 10, Very good, (1007)
"Great location, clean hotel, good bar and restaurant "
The price is €87
includes taxes & fees
29 Jun - 30 Jun
San Antonio Marriott Northwest Medical Center
OYO Inn & Suites Medical Center San Antonio
Exterior

OYO Inn & Suites Medical Center San Antonio

2.0 star property
7.2 out of 10, Good, (210)
"Beautiful place to stay love it "
The price is €71
includes taxes & fees
24 Jun - 25 Jun
OYO Inn & Suites Medical Center San Antonio
Studio 6 San Antonio, Tx - Northwest Medical Center
Desk, laptop workspace, blackout curtains, free WiFi

Studio 6 San Antonio, Tx - Northwest Medical Center

2.0 star property
7.0 out of 10, Good, (147)
"Nice place "
The price is €46
includes taxes & fees
6 Jul - 7 Jul
Studio 6 San Antonio, Tx - Northwest Medical Center
Atria Inn & Suites
Front of property

Atria Inn & Suites

2.0 star property
7.6 out of 10, Good, (226)
"I like that the staff is extremely kind and the "
The price is €50
includes taxes & fees
15 Jul - 16 Jul
Atria Inn & Suites
Studio 6 San Antonio, TX - Medical Center
1 bedroom, desk, laptop workspace, free WiFi

Studio 6 San Antonio, TX - Medical Center

2.0 star property
6.6 out of 10, (717)
"Good location for medical visit."
The price is €56
includes taxes & fees
26 Jun - 27 Jun
Studio 6 San Antonio, TX - Medical Center
Motel 6 San Antonio, TX - Northwest Medical Center
Free WiFi, bed sheets

Motel 6 San Antonio, TX - Northwest Medical Center

2.0 star property
6.0 out of 10, (1001)
"It was very clean and nice and quiet."
The price is €42
includes taxes & fees
29 Jun - 30 Jun
Motel 6 San Antonio, TX - Northwest Medical Center
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Free daily on-the-go breakfast

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

3.0 star property
6.6 out of 10, (1002)
"Quick check in and great breakfast"
The price is €72
includes taxes & fees
29 Jun - 30 Jun
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Flex Studios
Basic Room, Multiple Beds, Non Smoking

Flex Studios

2.5 star property
6.0 out of 10, (468)
"The staff was very helpful and accommodating. And they were super friendly!"
The price is €53
includes taxes & fees
24 Jun - 25 Jun
Flex Studios
The Westin San Antonio North
Indoor pool, outdoor pool

The Westin San Antonio North

4.0 star property
8.6 out of 10, Excellent, (1005)
"We enjoyed our stay and staff was great."
The price is €98
includes taxes & fees
3 Jul - 4 Jul
The Westin San Antonio North
Sonesta ES Suites San Antonio Northwest - Medical Center
Exterior

Sonesta ES Suites San Antonio Northwest - Medical Center

3.0 star property
8.0 out of 10, Very good, (1010)
"Excellent stay"
The price is €84
includes taxes & fees
13 Jul - 14 Jul
Sonesta ES Suites San Antonio Northwest - Medical Center
Extended Stay America Suites San Antonio Colonnade Medical
Lobby

Extended Stay America Suites San Antonio Colonnade Medical

2.5 star property
7.0 out of 10, Good, (818)
"It was great! Plenty of room and very nice staff."
The price is €69
includes taxes & fees
24 Jun - 25 Jun
Extended Stay America Suites San Antonio Colonnade Medical
Hyatt Place San Antonio-Northwest/Medical Center
Lobby sitting area

Hyatt Place San Antonio-Northwest/Medical Center

3.0 star property
8.0 out of 10, Very good, (1004)
"Nice place to stay. Will stay here again "
The price is €99
includes taxes & fees
29 Jun - 30 Jun
Hyatt Place San Antonio-Northwest/Medical Center
Best Western Medical Center North Inn & Suites Near Six Flags
Iron/ironing board, free cots/infant beds, rollaway beds, free WiFi

Best Western Medical Center North Inn & Suites Near Six Flags

2.5 star property
8.2 out of 10, Very good, (1430)
"Awesome stay "
The price is €68
includes taxes & fees
29 Jun - 30 Jun
Best Western Medical Center North Inn & Suites Near Six Flags
Best Western near Lackland AFB/SeaWorld
Exterior

Best Western near Lackland AFB/SeaWorld

2.5 star property
8.0 out of 10, Very good, (1012)
"This property was very clean and the staff was super friendly. Great location! "
The price is €60
includes taxes & fees
29 Jun - 30 Jun
Best Western near Lackland AFB/SeaWorld
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District
San Antonio River Walk showing a river or creek, a bridge and heritage architecture
Downtown San Antonio map

Downtown San Antonio

A scenic riverfront great entertainment and top sights from San Antonio River to Alamo – discover Downtown San Antonio, a destination also famous for its historic sites.

Far West Side map

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Uptown map

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.

Stone Oak map

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Northwest Side map

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Frequently asked questions

What is Medical Center District like?

Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.

What's a favourite hotel to stay in Medical Center District?

Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favourite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.

How many hotels will I be able to find in Medical Center District?

Expedia has 123 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.

What can I see and do in this San Antonio neighbourhood?

USAA Corporate Office Headquarters, Cinemark San Antonio 16 and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and First Unitarian Universalist Church are also worth a visit when you're out sightseeing in San Antonio.