![](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=300&q=medium)
Santa Cruz Holidays
- Plan, book, travel with confidence
Better together
Save up to €185 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top hotels in Santa Cruz
![InterContinental Presidente Mexico City, an IHG Hotel](https://images.trvl-media.com/lodging/1000000/10000/4700/4641/30bc28af_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
InterContinental Presidente Mexico City, an IHG Hotel
Campos Eliseos 218, Mexico City
The price is €358 per night from 1 Mar to 2 Mar
€358
includes taxes & fees
1 Mar - 2 Mar
9.2/10 Wonderful! (1,600 reviews)
"We had a wonderful time"
Reviewed on 15 Feb 2025
![Hotel Polanco](https://images.trvl-media.com/lodging/17000000/16830000/16828300/16828214/f7110252_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Hotel Polanco
Edgar Allan Poe 8, Col Polanco, Mexico City, CDMX
7.8/10 Good! (442 reviews)
"Housekeeping very nice Close to a very good restaurant area"
Reviewed on 7 Dec 2024
![Hyatt Regency Mexico City](https://images.trvl-media.com/lodging/1000000/30000/23400/23360/38ad8541_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Hyatt Regency Mexico City
Campos Eliseos No. 204 Polanco, Chapultepec, Mexico City
Fully refundableReserve now, pay when you stay
The price is €278 per night from 22 Feb to 23 Feb
€278
includes taxes & fees
22 Feb - 23 Feb
9.2/10 Wonderful! (1,007 reviews)
"Extraordinary service"
Reviewed on 13 Feb 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit
![Tula de Allende](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/201000/201771-Museo-Nacional-Del-Virreinato.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
National Museum of the Viceroyalty
Marvel at the dazzling exhibitions of well-preserved colonial art on display inside one of Mexico’s finest examples of Baroque architecture.
What to do in Santa Cruz
![The guide narrating the Stories and Legends of the People of Tepotzotlán](https://mediaim.expedia.com/localexpert/3013268/c0c5f5e0-f4f4-43b4-906c-4ba846cbfc76.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Pedestrian tour of the Center and Visit to the National Museum of the Viceroyalty
€15
per traveller
![Steer route: Tour of the ruins and tasting in Mazatan](https://mediaim.expedia.com/localexpert/48093422/e41257ac-103e-4f7b-b2e2-67e1556da9e6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Steer route: Tour of the ruins and tasting in Mazatan
€138
per adult
![Polaris Razor Jungle Adventure & Beach Getaway](https://mediaim.expedia.com/localexpert/46707083/09ff18f6-b305-46a5-82a5-754d6e38da39.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Cozumel Razor Expeditions: Jungle & Beach getaway
€123
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.