Photo by Sarah Mack

Santiago Island Hotels

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Tonight
24 Apr - 25 Apr
Tomorrow
25 Apr - 26 Apr
This weekend
25 Apr - 27 Apr
Next weekend
2 May - 4 May

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Santiago Island hotels

Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Santiago Island

Trip time! Discover the island views and natural setting in Santiago Island.

See all hotels in Santiago Island
Photo by Sarah Mack
Open Photo by Sarah Mack

Frequently asked questions

If I need to cancel my hotel reservation in Santiago Island, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Filter your search by free cancellation to find flexible hotel deals in Santiago Island.

What is staying in Santiago Island like?

Visitors can enjoy all that Santiago Island has to offer, including its parks. A top sight in the city is Galapagos National Park. Find out more about Santiago Island.

What are the top places to visit in Santiago Island?

The picturesque setting of Galapagos National Park and Mosquera Island exemplify the area's natural beauty. Additionally, you might want to add Puerto Egas to your itinerary. Take a look at what more there is to see and do in Expedia's Santiago Island guide.

What's the seasonal weather like in Santiago Island?

The hottest months are usually January and February, with an average temperature of 29°C, while the coldest months are August and September, with an average of 23°C. Average annual precipitation for Santiago Island is 598 mm.