Southern Illinois Holidays

  • Plan, book, travel with confidence

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    Better together
    Save up to €185 when you book a flight and hotel together*
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    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy
    Plan, book, and manage your trip all in one place

Where to stay in Southern Illinois

Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
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Eastport

While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.

Find hotels in Eastport

Top hotels in Southern Illinois

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is €99 per night from 19 Apr to 20 Apr
€99
includes taxes & fees
19 Apr - 20 Apr
9.6/10 Exceptional! (1,291 reviews)
"Very clean, friendly and helpful staff, amenities as described"

Reviewed on 13 Apr 2025

Drury Plaza Hotel Mt. Vernon
Super 8 by Wyndham O'Fallon
Super 8 by Wyndham O'Fallon
2 out of 5
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
The price is €56 per night from 23 Apr to 24 Apr
€56
includes taxes & fees
23 Apr - 24 Apr
7.6/10 Good! (1,002 reviews)
"service was very friendly. easy location very dated but was clean reasonable place to stay out the storms as we were traveling"

Reviewed on 12 Apr 2025

Super 8 by Wyndham O'Fallon
Quality Inn & Suites near St. Louis and I-255
Quality Inn & Suites near St. Louis and I-255
2.5 out of 5
1607 Pontiac Dr, East St. Louis, IL
Fully refundableReserve now, pay when you stay
The price is €67 per night from 23 Apr to 24 Apr
€67
includes taxes & fees
23 Apr - 24 Apr
7.4/10 Good! (1,001 reviews)
"No problems"

Reviewed on 14 Apr 2025

Quality Inn & Suites near St. Louis and I-255
See all 978 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Southern Illinois holiday package cost?
From just , you can tailor make your Southern Illinois holiday package. Simply bundle hotels, flights and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Southern Illinois?
Bundle your flights and hotels with Expedia to save big on your next big adventure. With over 550 airlines and 1,000,000 hotels globally, your Southern Illinois holiday package can be tailored exactly to suit your budget. With all that extra money, why not throw in one or more awesome activities and tours? It’s an easy way to unlock even more discounts. Your dream getaway to Southern Illinois is much closer than you thought!
What are the top hotels in Southern Illinois?
Take a look at Super 8 by Wyndham Carbondale and Best Western Saluki Inn. They’re top picks for lots of travellers to Carbondale. If Marion is on your travel itinerary, Super 8 by Wyndham Marion and Quality Inn And Suites are a couple of popular options.
How far in advance should I book my Southern Illinois holiday?
Reward yourself with the widest variety at the lowest prices by booking your holiday to Southern Illinois early. Air carriers usually sell flight tickets around 12 months before departure, so reserve your spot ASAP. That said, Expedia is dedicated to giving you the best bargains around, so it’s never a bad time to book your dream holiday!
What does an Expedia Southern Illinois travel package include?
That depends on what sort of trip you’re contemplating. Southern Illinois holiday deals can include flights, hotels and car rentals. You can mix and match to create the travel package that suits you. You can also add on experiences and activities after you’ve booked to get even bigger discounts.
What should I know before booking a Southern Illinois travel package?
You’ll score excellent savings when you combine your flights, hotels and rental cars into a package. Not only that, booking everything in one spot will make your trip planning easier. So why waste your money or time? Whether you’re organising a ritzy city getaway or a low-cost family road trip, explore our holiday packages today.
Can I choose my airline with a Southern Illinois Expedia holiday package?
You can, and with more than 550 airlines to pick from across the globe, you’re not short on choice. Browse the available options and see which airline fits your needs and budget.
If I'm not able to travel, can I cancel my Southern Illinois holiday package?
You can cancel your Southern Illinois booking if your plans have changed. Whether you’ll be charged a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.

Popular places to visit

Superman Statue featuring a statue or sculpture as well as a small group of people

Superman Statue

Superman fans will love getting a photograph taken in front of this giant statue of the Man of Steel himself, dressed in his iconic red-and-blue guise.

Superman Statue
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.