American Airlines Cheap Flights from Buffalo to San Diego

View €133 flight on Thu, 4 Sep 2025Opens in a new window

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Prices were available within the past 7 days and start at €133 for one-way flights and €256 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, 4 Sep - Wed, 10 Sep
BUF
Buffalo
SAN
San Diego
€256 Return, found 2 days ago
€256
Return
found 2 days ago
Select American Airlines flight, departing Thu, 4 Sep from Buffalo to San Diego, returning Wed, 10 Sep, priced at €256 found 2 days ago
American Airlines
Thu, 4 Sep - Wed, 10 Sep
BUF
Buffalo
SAN
San Diego
€265 Return, found 2 days ago
€265
Return
found 2 days ago
Select American Airlines flight, departing Thu, 4 Sep from Buffalo to San Diego, returning Wed, 10 Sep, priced at €265 found 2 days ago
American Airlines
Thu, 4 Sep - Wed, 10 Sep
BUF
Buffalo
SAN
San Diego
€266 Return, found 2 days ago
€266
Return
found 2 days ago
Select American Airlines flight, departing Thu, 4 Sep from Buffalo to San Diego, returning Wed, 10 Sep, priced at €266 found 2 days ago
American Airlines
Thu, 4 Sep - Wed, 10 Sep
BUF
Buffalo
SAN
San Diego
€274 Return, found 2 days ago
€274
Return
found 2 days ago
Select American Airlines flight, departing Thu, 4 Sep from Buffalo to San Diego, returning Wed, 10 Sep, priced at €274 found 2 days ago
American Airlines
Thu, 4 Sep - Wed, 10 Sep
BUF
Buffalo
SAN
San Diego
€278 Return, found 2 days ago
€278
Return
found 2 days ago
Select American Airlines flight, departing Thu, 4 Sep from Buffalo to San Diego, returning Wed, 10 Sep, priced at €278 found 2 days ago
American Airlines
Thu, 4 Sep - Wed, 10 Sep
BUF
Buffalo
SAN
San Diego
€279 Return, found 2 days ago
€279
Return
found 2 days ago
Select American Airlines flight, departing Thu, 4 Sep from Buffalo to San Diego, returning Wed, 10 Sep, priced at €279 found 2 days ago
American Airlines
Thu, 4 Sep - Wed, 10 Sep
BUF
Buffalo
SAN
San Diego
€295 Return, found 2 days ago
€295
Return
found 2 days ago
Select American Airlines flight, departing Thu, 4 Sep from Buffalo to San Diego, returning Wed, 10 Sep, priced at €295 found 2 days ago
American Airlines
Thu, 4 Sep - Wed, 10 Sep
BUF
Buffalo
SAN
San Diego
€312 Return, found 2 days ago
€312
Return
found 2 days ago
Select American Airlines flight, departing Thu, 4 Sep from Buffalo to San Diego, returning Wed, 10 Sep, priced at €312 found 2 days ago
American Airlines
Thu, 4 Sep - Wed, 10 Sep
BUF
Buffalo
SAN
San Diego
€325 Return, found 2 days ago
€325
Return
found 2 days ago
Select American Airlines flight, departing Thu, 4 Sep from Buffalo to San Diego, returning Wed, 10 Sep, priced at €325 found 2 days ago
Buffalo to San Diego route information
Origin airport
Buffalo Niagara Intl.
Destination airport
San Diego Intl.
Distance
3507 km
*Available to Expedia members.