Featured airlines
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 15% on select hotels after you book a flight*
- Brussels to Panama City
- Paris to Panama City
- Amsterdam to Panama City
- Istanbul to Panama City
- Sofia to Panama City
- Warsaw to Panama City
- Berlin to Panama City
- Dublin to Panama City
- Barranquilla to Panama City
- Vienna to Panama City
- Baltimore to Panama City
- Cartagena to Panama City
- Venice to Panama City
Expedia's Latest Trends
Hotels
MedPlaya Hotel Alba BeachThe Twelve HotelThe Chelsea Harbour Hotel and SpaRockview HouseInturotel Cala AzulHistoric Hotels in County WicklowLaragh HouseCrowne Plaza Seattle - Downtown by IHGLoews Hollywood HotelApartments County WaterfordHotels in RosscahillBungalows Doña RosaHotel PaganiniHistoric Hotels in KilkeeHotels in MarrakechHotels in GoleenHotels with Childcare in SpainHotels with Spa in County Laois
Flights
Activities
Packages
Holiday Rentals
*Available to Expedia members.