Cheap Flights from Detroit to Palo Alto

View €124 flight on Thu, 8 May 2025Opens in a new window

Popular airlines from Detroit to Palo Alto

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 15% on select hotels after you book a flight*
  • payments icon
    Earn twice
    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Detroit to Palo Alto (DTT-SJC)

Prices were available within the past 7 days and start at €124 for one-way flights and €254 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Thu, 8 May - Wed, 14 May
DTW
Detroit
SFO
San Francisco
€254 Return, found 1 day ago
€254
Return
found 1 day ago
Select JetBlue Airways flight, departing Thu, 8 May from Detroit to San Francisco, returning Wed, 14 May, priced at €254 found 1 day ago
Delta
Fri, 30 May - Mon, 2 Jun
DTW
Detroit
SFO
San Francisco
€255 Return, found 17 hours ago
€255
Return
found 17 hours ago
Select Delta flight, departing Fri, 30 May from Detroit to San Francisco, returning Mon, 2 Jun, priced at €255 found 17 hours ago
Delta
Thu, 22 May - Tue, 27 May
DTW
Detroit
SFO
San Francisco
€264 Return, found 5 days ago
€264
Return
found 5 days ago
Select Delta flight, departing Thu, 22 May from Detroit to San Francisco, returning Tue, 27 May, priced at €264 found 5 days ago
Delta
Fri, 2 May - Sun, 4 May
DTW
Detroit
SFO
San Francisco
€265 Return, found 6 days ago
€265
Return
found 6 days ago
Select Delta flight, departing Fri, 2 May from Detroit to San Francisco, returning Sun, 4 May, priced at €265 found 6 days ago
American Airlines
Thu, 1 May - Wed, 7 May
DTW
Detroit
SFO
San Francisco
€272 Return, found 6 days ago
€272
Return
found 6 days ago
Select American Airlines flight, departing Thu, 1 May from Detroit to San Francisco, returning Wed, 7 May, priced at €272 found 6 days ago
United
Thu, 8 May - Wed, 14 May
DTW
Detroit
SFO
San Francisco
€344 Return, found 1 day ago
€344
Return
found 1 day ago
Select United flight, departing Thu, 8 May from Detroit to San Francisco, returning Wed, 14 May, priced at €344 found 1 day ago
*Available to Expedia members.