Cheap Flights from Rome to San Diego

  • Plan, book, fly with confidence
  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 15% on select hotels after you book a flight*
  • payments icon
    Earn twice
    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Rome to San Diego (ROM-SAN)

Prices were available within the past 7 days and start at €774 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

*Available to Expedia members.