Featured airlines

- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 15% on select hotels after you book a flight*
Cheap flights from Prague to Southampton (PRG-SOU)
Prices were available within the past 7 days and start at €239 for one-way flights and €392 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, 12 Apr - Wed, 16 Apr
PRG
Prague
SOU
Southampton
€392 Return, found 2 hours ago
€392
Return
found 2 hours ago

Wed, 9 Apr - Sun, 13 Apr
PRG
Prague
SOU
Southampton
€492 Return, found 2 days ago
€492
Return
found 2 days ago

Wed, 9 Apr - Sun, 13 Apr
PRG
Prague
SOU
Southampton
€507 Return, found 2 days ago
€507
Return
found 2 days ago

Sat, 12 Apr - Wed, 16 Apr
PRG
Prague
SOU
Southampton
€508 Return, found 2 hours ago
€508
Return
found 2 hours ago

Wed, 9 Apr - Sun, 13 Apr
PRG
Prague
SOU
Southampton
€531 Return, found 2 days ago
€531
Return
found 2 days ago

Wed, 9 Apr - Sun, 13 Apr
PRG
Prague
SOU
Southampton
€553 Return, found 2 days ago
€553
Return
found 2 days ago
Top Routes to Southampton
Expedia's Latest Trends
Hotels
Flights
Cars
Packages
Holiday Rentals
*Available to Expedia members.