Featured airlines
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 15% on select hotels after you book a flight*
- Newark to Panama City
- Bangkok to Panama City
- London to Panama City
- Brussels to Panama City
- Istanbul to Panama City
- Warsaw to Panama City
- Barcelona to Panama City
- Dublin to Panama City
- Budapest to Panama City
- Madrid to Panama City
- Lima to Panama City
- Vienna to Panama City
- Cartagena to Panama City
- Bogotá to Panama City
Expedia's Latest Trends
Hotels
Sheraton Grand London Park LaneFamily Friendly Hotels in AlbaniaCheap Hotels in NashvilleLGBT-Friendly Hotels in BangkokHotels in Innere StadtHotels in ManorhamiltonAl Raha Beach HotelApartments Neufahrn bei FreisingBeach Hotels in SandyfordHistoric Hotels in TraleeKillarney Avenue HotelApartments AdamstownCaravan Parks LanzaroteHotels in Hell's KitchenGlasson LakeHouseParkview HotelHotels near Croagh Patrick
Flights
Activities
Packages
*Available to Expedia members.