Mission Valley Hotel Guide - Hotels with Spa in Mission Valley, San Diego

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Mission Valley Hotels with Spa

Tonight
29 Jul - 30 Jul
Tomorrow
30 Jul - 31 Jul
This weekend
1 Aug - 3 Aug
Next weekend
8 Aug - 10 Aug

Top Mission Valley Hotels with Spa

Town and Country San Diego
Relax by the hotel's central pool surrounded by lounge chairs and lush greenery.

Town and Country San Diego

4.0 star property
8.6 out of 10, Excellent, (1242)
"Overall great stay"
The price is €214
includes taxes & fees
4 Aug - 5 Aug
Town and Country San Diego
San Diego Marriott Mission Valley
Relax in style with a fire pit table surrounded by comfortable seating and a stunning pool view.

San Diego Marriott Mission Valley

4.0 star property
8.6 out of 10, Excellent, (1008)
"We like the rooms, the pool, the friendly staff, the great food."
The price is €160
includes taxes & fees
3 Aug - 4 Aug
San Diego Marriott Mission Valley
Hotel Iris - San Diego
Hotel Iris features a modern design with a flat roof and lush gardens.

Hotel Iris - San Diego

2.5 star property
5.8 out of 10, (1010)
"Nice staff clean room"
The price is €79
includes taxes & fees
24 Aug - 25 Aug
Hotel Iris - San Diego
Mission View Inn & Suites San Diego Sea World - Zoo
Surrounded by lush greenery, this hotel offers a convenient parking area and multiple levels with balconies.

Mission View Inn & Suites San Diego Sea World - Zoo

2.5 star property
6.0 out of 10, (670)
"Close to everything, clean. My favorite part is the convenience of online amenities"
Mission View Inn & Suites San Diego Sea World - Zoo
Kings Inn San Diego
Relax in the hotel's central seating area, surrounded by a staircase and reception desk.

Kings Inn San Diego

2.5 star property
8.8 out of 10, Excellent, (3365)
"Great stay and fun vibe!"
Kings Inn San Diego
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Two single beds and a large bed with dark headboards and white bedding, a desk, and a flat-screen TV.

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.5 star property
8.0 out of 10, Very good, (1875)
"good breakfast room was nice and clean not too far from beach."
The price is €159
includes taxes & fees
24 Aug - 25 Aug
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Sheraton Mission Valley San Diego Hotel
Guests can dine al fresco under shaded tables and umbrellas, surrounded by lush greenery and palm trees.

Sheraton Mission Valley San Diego Hotel

4.0 star property
8.6 out of 10, Excellent, (1458)
"Great Hotel"
The price is €134
includes taxes & fees
3 Aug - 4 Aug
Sheraton Mission Valley San Diego Hotel
Handlery Hotel
Relax by the resort's large pool surrounded by lounge chairs and umbrellas, set amidst lush palm trees and tropical plants.

Handlery Hotel

3.5 star property
8.2 out of 10, Very good, (1928)
"The pool area is great and I loved the convenience of the restaurants. "
The price is €108
includes taxes & fees
10 Aug - 11 Aug
Handlery Hotel
DoubleTree by Hilton San Diego - Hotel Circle
Relax by the pool surrounded by palm trees and lounge chairs with cushions, with a fire pit and umbrellas for shade.

DoubleTree by Hilton San Diego - Hotel Circle

4.0 star property
7.4 out of 10, Good, (1641)
"Friendly staff"
The price is €123
includes taxes & fees
13 Aug - 14 Aug
DoubleTree by Hilton San Diego - Hotel Circle
Legacy Resort Hotel & Spa
Welcome to our hotel, set amidst beautifully maintained gardens with a clear path leading to the main building.

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2895)
"Great stay"
The price is €130
includes taxes & fees
24 Aug - 25 Aug
Legacy Resort Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mission Valley Hotel Reviews

Handlery Hotel

Handlery Hotel

10/10 Excellent
"If you are going to Disney is a very walkable distance to the park . Beds were very comfortable , and room was clean. Overall it was a great stay. "
Alejandra 1-night trip
Posted 18 hours ago
Handlery Hotel

Frequently asked questions

Looking to holiday at a spa hotel in Mission Valley?
Treat yourself to some pampering and book a hotel with a spa. Travellers love the historical sites and shops in Mission Valley. Enjoy the museums and beaches during your holiday. Spa hotels are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Mission Valley?
Handlery Hotel is a top spa hotel featuring a fitness centre, a hair salon and an outdoor pool. Spend an afternoon at the spa where you'll find facials and massage treatments. Another popular spa hotel in Mission Valley is Legacy Resort Hotel & Spa.
How many spa hotels are there in Mission Valley?
Among Expedia's 112 accommodation options in Mission Valley, there are 2 spa hotels.
What's there to see and do in Mission Valley?
Enjoy all that Mission Valley has to offer and visit Fashion Valley Mall, Snapdragon Stadium and Mission Valley Mall. If you have extra time while you're in the area, you might want to stop by Riverwalk Golf Club and San Diego Zoo.
What is a Mission Valley spa hotel?
Spa hotels in Mission Valley have on-site spas which offer services such as therapies and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on holiday.