Río Sereno Hotels

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Río Sereno hotels

Hotel Finca Lerida

3.0 star property
8.8 out of 10, Excellent, (175)
"Best place in Panama. We drove from Panama City eight hours but worth it We loved the national park feel hiked the trails (even to the waterfall) had great food and the best coffee, Ask Roosevelt in the dining room how he got his name. Don’t miss this place"
The price is €238
includes taxes & fees
20 Feb - 21 Feb
Hotel Finca Lerida

Risco de Hugo

2.0 star property
The price is €136
includes taxes & fees
17 Feb - 18 Feb
Risco de Hugo

Los Quetzales Ecolodge & Spa

3.0 star property
8.6 out of 10, Excellent, (24)
"We were there just one night. Got there past 8 pm, hungry and the restaurant was already closed, didn’t get much help from the staff. It took them half an hour to charge my credit card for the cost of the room and we had to drive 20 minutes, back to the city, to find a place to eat. Back at the room it was cozy with a fire place. It was really cold, loved it. We had a great sleep. In the morning, I was amazed by the place, the gardens, the mountains and town, the breakfast, the coffee, the main...
The price is €92
includes taxes & fees
5 Mar - 6 Mar
Los Quetzales Ecolodge & Spa

Hotel Bambito By Faranda Boutique, a member of Radisson Individuals

3.0 star property
8.0 out of 10, Very good, (209)
"Just awesome "
The price is €141
includes taxes & fees
4 Mar - 5 Mar
Hotel Bambito By Faranda Boutique, a member of Radisson Individuals

Los Brezos Boutique Hotel

3.5 star property
9.4 out of 10, Exceptional, (19)
"This is a great hotel and very much recommend. The food was great and the service was outstanding."
The price is €138
includes taxes & fees
19 Feb - 20 Feb
Los Brezos Boutique Hotel

Hostal Victoria Volcán Chiriquí S. A.

2.0 star property
8.6 out of 10, Excellent, (7)
"I found it to be a comfortable and friendly place. Snacks and coffee available, and walkable to dining options. I liked the large display with local activities mapped. "
The price is €52
includes taxes & fees
17 Feb - 18 Feb
Hostal Victoria Volcán Chiriquí S. A.

Hotel Dos Rios

3.0 star property
8.6 out of 10, Excellent, (61)
"The hotel is being updated so it will be even better in the future, the restaurant and grounds are great!"
The price is €84
includes taxes & fees
2 Mar - 3 Mar
Hotel Dos Rios
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Río Sereno
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Río Sereno

Head to sights like La Amistad International Park as you discover the local area in Río Sereno.

Frequently asked questions

What's the best place for a stay in Río Sereno?

Located 2 mi (3.2 km) from the heart of Río Sereno, Glamping on a coffee plantation on the Panama Costa Rica broder. is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Hotel Bambito By Faranda Boutique, a member of Radisson Individuals and Los Quetzales Ecolodge & Spa. See all available top hotels, or vacation rentals in Río Sereno.

What are some of the best holiday rentals that Río Sereno has to offer?

Casa Camila: This holiday home rental outside Río Sereno offers a terrace, a garden and Netflix to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop and a microwave. See all vacation rentals in Río Sereno.

If I need to cancel my hotel reservation in Río Sereno, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Río Sereno.

What's it like staying in Río Sereno?

Those travelling to Río Sereno will definitely enjoy the sights to see and things to do. There are 32 hotels and other accommodation options in the surrounding area. Find out more about Río Sereno.

What should I see while I'm in Río Sereno?

A favourite place to visit is La Amistad International Park. You'll also find Wilson Botanical Garden and Barriles in the area. Take a look at what more there is to see and do in Expedia's Río Sereno guide.

What's the weather like in Río Sereno?

The hottest months are usually March and February, with an average temperature of 25°C, while the coldest months are January and February, with an average of 24°C. The rainiest months in Río Sereno are October, August, November and July, with each month seeing an average of 853 mm of rainfall.