Featured airlines
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 15% on select hotels after you book a flight*
- Newark to Panama City
- Raleigh to Panama City
- London to Panama City
- Brussels to Panama City
- Paris to Panama City
- New York to Panama City
- Amsterdam to Panama City
- Istanbul to Panama City
- Berlin to Panama City
- Dublin to Panama City
- Madrid to Panama City
- Vienna to Panama City
- Venice to Panama City
- Santiago to Panama City
- Belfast to Panama City
Expedia's Latest Trends
Hotels
Historic Hotels in SalthillHotels with Pool in County MayoB&B KilmallockHotels near Frankfurt Christmas MarketHotels in DublinWashington Square HotelHotels in AdamstownHotels in TenerifeHotels with Connecting Rooms in MálagaLeonardo Hotel BrightonVila São Vicente - Adults OnlyPestana Grand Premium Ocean ResortAll Inclusive Hotels in South AmericaNesbitt Arms Boutique HotelDingle Benners HotelHotels with Restaurant in County MeathTownhouse on the GreenVincci Mercat Hotel
Flights
Activities
*Available to Expedia members.