Featured airlines

- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 15% on select hotels after you book a flight*
- Raleigh to Panama City
- Brussels to Panama City
- Prague to Panama City
- Amsterdam to Panama City
- Paris to Panama City
- Istanbul to Panama City
- Warsaw to Panama City
- Dublin to Panama City
- Madrid to Panama City
- Vienna to Panama City
- Rome to Panama City
- Frankfurt to Panama City
- Nashville to Panama City
- Cartagena to Panama City
- Venice to Panama City
- Austin to Panama City
Expedia's Latest Trends
Hotels
Hotel Excelsior San MarcoHotels in BlanchardstownLong Quay HouseMelia Calviá BeachKillarney Towers Hotel & Leisure CentreWoodford Dolmen HotelHotels in Blasket IslandsViva SunriseHotel Riu Costa del SolHotel Laguna Park & Aqua ClubHotels near Southmead HospitalCheap Hotels in Amsterdam City CentreFour Points Flex by Sheraton London Shoreditch East
Flights
Holiday Rentals
*Available to Expedia members.