Downtown San Francisco Hotel Guide - Business Hotels in Downtown San Francisco, San Francisco

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Top Downtown San Francisco Business Hotels

Club Quarters Hotel in San Francisco
Terrace/patio
Club Quarters Hotel in San Francisco
4.0 star property
8.8 out of 10, Excellent, (2050)
"Proximity!"
The price is €114
includes taxes & fees
25 Nov - 26 Nov
Club Quarters Hotel in San Francisco
San Francisco Marriott Marquis
Cocktail bar
San Francisco Marriott Marquis
4.0 star property
8.8 out of 10, Excellent, (1592)
"Exceded all expectations. Best conference Hotel yet"
The price is €222
includes taxes & fees
22 Dec - 23 Dec
San Francisco Marriott Marquis
Hilton San Francisco Union Square
Exterior detail
Hilton San Francisco Union Square
4.0 star property
8.2 out of 10, Very good, (1096)
"Not clean"
The price is €185
includes taxes & fees
22 Dec - 23 Dec
Hilton San Francisco Union Square
Stanford Court San Francisco
Skyline Studio, 2 Double Beds | City view
Stanford Court San Francisco
4.0 star property
9.0 out of 10, Wonderful, (1089)
"Enjoyed my stay"
The price is €204
includes taxes & fees
26 Nov - 27 Nov
Stanford Court San Francisco
Grand Hyatt San Francisco
Restaurant
Grand Hyatt San Francisco
4.0 star property
8.8 out of 10, Excellent, (1004)
"Excellent"
The price is €191
includes taxes & fees
26 Nov - 27 Nov
Grand Hyatt San Francisco
InterContinental San Francisco, an IHG Hotel
Exterior
InterContinental San Francisco, an IHG Hotel
4.0 star property
9.0 out of 10, Wonderful, (1002)
"View from room just ok. Shower had hair on wall. Room service was insanely expensive delivery fee and tax "
The price is €192
includes taxes & fees
27 Nov - 28 Nov
InterContinental San Francisco, an IHG Hotel
Hyatt Regency San Francisco
Studio, Bay View
Hyatt Regency San Francisco
4.0 star property
9.2 out of 10, Wonderful, (1774)
"Had a wonderful stay"
The price is €194
includes taxes & fees
22 Dec - 23 Dec
Hyatt Regency San Francisco
Hotel Whitcomb
Lobby
Hotel Whitcomb
2.5 star property
7.4 out of 10, Good, (1002)
"The hotel is a bit old. It's great if you're looking to stay in a property with a historical aspect. Check-in was troubling. I don't recall on the Hotel's description here on Expedia or on their own website that the deposit was $400 up front. I stayed for 6 days so that should have been around $170. The room I stayed in was okay. The bathroom was small and the furniture was peeling. How you watch TV in the room was a little new which was appealing. You use a Chromecast and then just link your...
Hotel Whitcomb
Hotel Nikko San Francisco
Front of property – evening/night
Hotel Nikko San Francisco
4.5 star property
9.2 out of 10, Wonderful, (2082)
"Really kind staff, and very welcoming. Room was immaculate and i noticed the attention to the details. "
The price is €203
includes taxes & fees
25 Nov - 26 Nov
Hotel Nikko San Francisco
Chancellor Hotel on Union Square
Lobby sitting area
Chancellor Hotel on Union Square
3.5 star property
9.2 out of 10, Wonderful, (2391)
"We stayed for 3 days 2 nights and it was very convenient as it was a walking distance to the union square, lots of restaurants, and shopping mall in the area. The best part of our stay was the bed it was very soft and relaxing that I already slept at 7PM. Best sleep of my life! Exceptional customer service and will definitely come back again. "
The price is €115
includes taxes & fees
25 Nov - 26 Nov
Chancellor Hotel on Union Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Downtown San Francisco

Frequently asked questions

Why book your business-friendly hotel in Downtown San Francisco with Expedia?
With amenities like meeting rooms, housekeeping and free parking, our business-friendly stays come with all you’ll need to close your big work deal — and then kick back! Enter your travel destination and preferred dates and we’ll help you plan everything else.
How can I find cheap business-friendly hotels in Downtown San Francisco?
When work takes you to Downtown San Francisco, our “business friendly” filter will help you find the perfect hotel. From dependable WiFi to conference spaces and in-room desks, they come with the amenities you need for a productive and comfortable stay. Another handy tip? Narrow your search by your preferred star rating and budget to view the cheapest stays.