San Diego Hotel Guide. Hotels in Serra Mesa, San Diego, United States of America

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Top Trending Hotels Near Serra Mesa, San Diego

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
7.6 out of 10, Good, (2015)
"The pool area was sweet and the rooms were neatly arranged "
The price is €96
includes taxes & fees
25 Dec - 26 Dec
Days Inn by Wyndham San Diego Hotel Circle

Lafayette Hotel & Club

4.0 star property
9.2 out of 10, Wonderful, (512)
"Awsome place fun vibe totally inclusive "
The price is €222
includes taxes & fees
24 Dec - 25 Dec
Lafayette Hotel & Club

Hilton San Diego Mission Valley

4.0 star property
7.8 out of 10, Good, (1366)
"Another great stay at Hilton. "
The price is €135
includes taxes & fees
29 Dec - 30 Dec
Hilton San Diego Mission Valley

Holiday Inn Express San Diego Downtown, an IHG Hotel

2.5 star property
8.4 out of 10, Very good, (1212)
"Great hotel in a nice location "
The price is €150
includes taxes & fees
24 Dec - 25 Dec
Holiday Inn Express San Diego Downtown, an IHG Hotel

Best Western Seven Seas

3.0 star property
7.6 out of 10, Good, (2551)
"Beautiful property but they are disorganized with housekeeping and room maintenance. "
The price is €91
includes taxes & fees
24 Dec - 25 Dec
Best Western Seven Seas

Marriott Vacation Club®, San Diego

3.5 star property
9.2 out of 10, Wonderful, (1008)
"The rooom was spacious clean, organized and had all the conceniences of home."
The price is €172
includes taxes & fees
6 Jan - 7 Jan 2025
Marriott Vacation Club®, San Diego

DoubleTree by Hilton Hotel San Diego - Mission Valley

4.0 star property
8.2 out of 10, Very good, (1045)
"Nice hotel great facilities easy transportation "
The price is €135
includes taxes & fees
30 Dec - 31 Dec
DoubleTree by Hilton Hotel San Diego - Mission Valley

Courtyard by Marriott San Diego Mission Valley/Hotel Circle

3.5 star property
8.2 out of 10, Very good, (1098)
"lovely stay! service was great and was such a wonderful place to stay for a nice vacation. super affordable and easy to book & close to everything!"
The price is €135
includes taxes & fees
3 Jan - 4 Jan 2025
Courtyard by Marriott San Diego Mission Valley/Hotel Circle

Sheraton Mission Valley San Diego Hotel

4.0 star property
8.4 out of 10, Very good, (1269)
"Thank you"
The price is €135
includes taxes & fees
29 Dec - 30 Dec
Sheraton Mission Valley San Diego Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

2.5 star property
8.0 out of 10, Very good, (85)
"Small room, bed average. Wouldn’t recommend if multiple people are in same room more than a night or two but fine for one person. Location is perfect however. "
The price is €113
includes taxes & fees
10 Jan - 11 Jan 2025
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.2 out of 10, Good, (1006)
"Good enough for my overnight stay "
The price is €83
includes taxes & fees
6 Jan - 7 Jan 2025
Howard Johnson by Wyndham National City/San Diego South

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1005)
"This is a simple no frills clean property for a good price. Complimentary breakfast is usual offerings like most. Does have a pool & I saw an employee testing the water twice during my stay. Mini fridge in my room worked well."
The price is €126
includes taxes & fees
30 Dec - 31 Dec
Lamplighter Inn & Suites at SDSU

Stay Classy Hostel

2.0 star property
9.4 out of 10, Exceptional, (549)
"Like it allot "
The price is €70
includes taxes & fees
30 Dec - 31 Dec
Stay Classy Hostel

TownePlace Suites by Marriott San Diego Downtown

3.0 star property
9.0 out of 10, Wonderful, (888)
"Went with children. The room was fantastic. The parking was tight, the most insane parking garage i have been in. Breakfast was good, small dining area. Check in was very smooth and check out was even easier. "
The price is €143
includes taxes & fees
5 Jan - 6 Jan 2025
TownePlace Suites by Marriott San Diego Downtown

Hilton Garden Inn San Diego Mission Valley Stadium

3.0 star property
8.0 out of 10, Very good, (1005)
"."
The price is €123
includes taxes & fees
29 Dec - 30 Dec
Hilton Garden Inn San Diego Mission Valley Stadium

Holiday Inn Express & Suites San Diego - Mission Valley, an IHG Hotel

2.5 star property
8.8 out of 10, Excellent, (1005)
"Staff friendly and helpful. "
The price is €137
includes taxes & fees
3 Jan - 4 Jan 2025
Holiday Inn Express & Suites San Diego - Mission Valley, an IHG Hotel

Springhill Suites San Diego Mission Valley

3.5 star property
9.2 out of 10, Wonderful, (1005)
"It was a nice stay. I just would’ve prefer to know that they charge $50/night for dogs and $26/day for parking. This was nowhere specified when I booked this hotel through Hotels.com. The only thing that it said I would be charged at reception was $150 for incidentals/deposit. "
The price is €150
includes taxes & fees
24 Dec - 25 Dec
Springhill Suites San Diego Mission Valley

Mission View Inn & Suites San Diego Sea World - Zoo

2.5 star property
6.2 out of 10, (451)
"It was a quick check in & the staff is super helpful. Nice spot to run away too for a quick get away."
The price is €103
includes taxes & fees
24 Dec - 25 Dec
Mission View Inn & Suites San Diego Sea World - Zoo

San Diego Downtown Lodge

2.0 star property
6.4 out of 10, (1002)
"Great location "
The price is €78
includes taxes & fees
24 Dec - 25 Dec
San Diego Downtown Lodge

Days Inn by Wyndham Mission Valley/SDSU

2.0 star property
5.6 out of 10, (1011)
"It has a full-sized fridge, and a stove top as well as dishwasher! This is a GREAT choice for longer stays, cooking your own food, and the room is extremely large for a hotel! It's about 15 minutes away from everything. Free breakfast!"
The price is €84
includes taxes & fees
25 Dec - 26 Dec
Days Inn by Wyndham Mission Valley/SDSU
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Serra Mesa
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

Where is the best place to stay in Serra Mesa?

For your stay in Serra Mesa, Cozy 2 bedroom unit with pool is one of the top choices based on our traveller data. Other good choices for your stay in the area include Centrally Located San Diego Condo w/Hot Tub & Pool and Central location - 3br/2ba. Stay weekly. Clean, safe, quiet. .

How many hotels can I expect to find in the Serra Mesa area?

Expedia has 32 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.

What can I see and do in this San Diego neighbourhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.