San Diego Hotel Guide. Hotels in Otay Mesa, San Diego, United States of America

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16 Jul - 17 Jul
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17 Jul - 18 Jul
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18 Jul - 20 Jul
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Top Trending Hotels Near Otay Mesa, San Diego

Sycuan Casino Resort
Relax by the resort pool surrounded by palm trees and a pebble bed.

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1398)
"Great place to stay beautiful casino! "
Sycuan Casino Resort
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Welcome to Holiday Inn Express & Suites, featuring a modern design with a lush entrance area and a prominent address sign.

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
7.8 out of 10, Good, (1394)
"Great stay, close to the Cross Border Xpress "
The price is €109
includes taxes & fees
10 Aug - 11 Aug
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Best Western Plus Island Palms Hotel & Marina
Welcome to our lobby, featuring a spacious area with a central counter, pendant lights, and a tropical mural.

Best Western Plus Island Palms Hotel & Marina

3.0 star property
8.8 out of 10, Excellent, (1547)
"Very comfortable beds, gorgeous water view, front desk staff was wonderful. "
The price is €128
includes taxes & fees
3 Aug - 4 Aug
Best Western Plus Island Palms Hotel & Marina
Bay Club Hotel & Marina
Enjoy a tranquil marina view from your balcony, complete with a table for two.

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (2711)
"The views and location were perfect! "
The price is €160
includes taxes & fees
3 Aug - 4 Aug
Bay Club Hotel & Marina
Quality Suites San Diego Otay Mesa
Relax by the pool with lounge chairs and umbrellas, surrounded by a low wall.

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1021)
"Very accommodating. We had to leave before official breakfast time but staff brought out food for us."
The price is €117
includes taxes & fees
17 Jul - 18 Jul
Quality Suites San Diego Otay Mesa
Ayres Hotel San Diego South - Chula Vista
Relax in a comfortable seating area surrounded by lush greenery and a bar.

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1081)
"The area was amazing, food & shopping options were right across the hotel which was very convenient. Amenities were great, complimentary breakfast had good options, and staff were friendly. "
The price is €173
includes taxes & fees
20 Jul - 21 Jul
Ayres Hotel San Diego South - Chula Vista
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Grand Central Hotel features a symmetrical facade with evenly spaced windows and a grand arched entrance.

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

4.0 star property
9.2 out of 10, Wonderful, (398)
"Great stay!"
The price is €134
includes taxes & fees
27 Jul - 28 Jul
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
La Quinta Inn by Wyndham San Diego Chula Vista
Experience the charm of this historic hotel, featuring a striking bell tower and sheltered entrance.

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1295)
"We loved the hotel and breakfast was nice too, great staff and nice hospitality, we will definitely come again."
The price is €122
includes taxes & fees
10 Aug - 11 Aug
La Quinta Inn by Wyndham San Diego Chula Vista
Best Western Plus Marina Gateway Hotel
Two large beds with blue and white bedding, a desk, and a potted plant adorn this stylish room.

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3120)
"This was our second time staying here and we loved it just as much as the first! Such a great hotel, friendly staff and a great location!"
The price is €144
includes taxes & fees
10 Aug - 11 Aug
Best Western Plus Marina Gateway Hotel
Best Western San Diego Pacific Beach/Mission Bay
Relax by the pool surrounded by palm trees and a building in the background.

Best Western San Diego Pacific Beach/Mission Bay

2.5 star property
7.2 out of 10, Good, (1235)
"Great place"
The price is €106
includes taxes & fees
29 Jul - 30 Jul
Best Western San Diego Pacific Beach/Mission Bay
Hampton Inn & Suites San Diego Point Loma
Beach nearby

Hampton Inn & Suites San Diego Point Loma

2.5 star property
8.0 out of 10, Very good, (1000)
"Great hotel "
Hampton Inn & Suites San Diego Point Loma
SpringHill Suites by Marriott Chula Vista Eastlake
Relax by the ocean with a clear view from this pool area, surrounded by lounge chairs and tables under the shade of palm trees.

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (372)
"Great location, Great Staff and really clean."
The price is €146
includes taxes & fees
10 Aug - 11 Aug
SpringHill Suites by Marriott Chula Vista Eastlake
Best Western Chula Vista/Otay Valley Hotel
Relax in a well-appointed room with a comfortable seating area, desk, and coffee station.

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1449)
"Very nice bed and very quiet y good breakfast in the morning "
The price is €120
includes taxes & fees
3 Aug - 4 Aug
Best Western Chula Vista/Otay Valley Hotel
Lamplighter Inn & Suites at SDSU
Relax by the pool surrounded by lounge chairs and umbrellas, with a lifeguard on duty.

Lamplighter Inn & Suites at SDSU

2.5 star property
9.2 out of 10, Wonderful, (1207)
"Nice place to stay "
Lamplighter Inn & Suites at SDSU
Best Western Americana Inn
Two large beds with white linens and wooden headboards, a flat-screen TV, and a desk with a lamp.

Best Western Americana Inn

2.5 star property
8.8 out of 10, Excellent, (1119)
"We really enjoy this hotel, it was clean and the service was excellent."
The price is €129
includes taxes & fees
29 Jul - 30 Jul
Best Western Americana Inn
Valli Hi Motel
Relax in a spacious room with a large bed, wooden desk, and comfortable seating area.

Valli Hi Motel

2.5 star property
8.2 out of 10, Very good, (1000)
"Was quiet and had no issues would stay again "
Valli Hi Motel
Palihotel San Diego Gaslamp Quarter
Relax on the rooftop with striped sofas and armchairs, surrounded by lush greenery and city views.

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.6 out of 10, Excellent, (1523)
"Excellent hotel!"
The price is €130
includes taxes & fees
29 Jul - 30 Jul
Palihotel San Diego Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Experience the vibrant city life from our corner location, with stunning views of the surrounding streets.

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
9.0 out of 10, Wonderful, (1002)
"Great location, good breakfast, clean rooms"
The price is €148
includes taxes & fees
20 Jul - 21 Jul
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Sea Harbor Hotel
Relax in a stylish room with two single beds, a large window offering a view of the outside, and a desk with a lamp and telephone.

Sea Harbor Hotel

2.0 star property
8.6 out of 10, Excellent, (892)
"Would definitely stay there again. ."
The price is €181
includes taxes & fees
16 Aug - 17 Aug
Sea Harbor Hotel
Legacy Resort Hotel & Spa
Welcome to our hotel, set amidst beautifully maintained gardens with a clear path leading to the main building.

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2905)
"Great place to stay! "
The price is €145
includes taxes & fees
6 Aug - 7 Aug
Legacy Resort Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Belmont Park which includes rides and a garden
Mission Beach map

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach featuring a beach
Pacific Beach map

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter featuring a city, signage and a bar
Gaslamp Quarter map

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach map

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.

How many hotels will I find in the Otay Mesa area?

Expedia has 5 Otay Mesa hotels and other accommodation options, and one might make a good home base for venturing out into the greater San Diego area.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! Most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.

What is there to do in this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.